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Opioid-free Anesthesia for Analgesic Dependence (OFA vs OA Trial)

Phase 2 & 3
Waitlist Available
Led By Enrico Camporesi, MD
Research Sponsored by University of South Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Summary

This trial looks at whether patients who have surgery for colorectal cancer have less pain and need fewer opioids when they are given opioid-free anesthesia.

Eligible Conditions
  • Analgesic Drug Dependence
  • Colectomy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Brief Pain Inventory
Post-surgical opioid prescription use, # of pills used per week
Secondary study objectives
Length of Stay
PACU: Nausea Scores
Morphine
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Opioid-free AnesthesiaExperimental Treatment1 Intervention
Patients will receive no intraoperative narcotics as part of their anesthesia regimen
Group II: Opioid AnesthesiaActive Control1 Intervention
Patients will receive intraoperative narcotics as part of their anesthesia regimen

Find a Location

Who is running the clinical trial?

University of South FloridaLead Sponsor
422 Previous Clinical Trials
189,127 Total Patients Enrolled
Enrico Camporesi, MDPrincipal InvestigatorUniversity of South Florida
1 Previous Clinical Trials
~15 spots leftby Sep 2025
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