← Back to Search

Other

AUR101 for Plaque Psoriasis (INDUS-3 Trial)

Phase 2
Waitlist Available
Research Sponsored by Aurigene Discovery Technologies Limited
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from day 1 through follow up visit at week 14

Summary

This trial is testing AUR101, a new medication, in patients with moderate-to-severe plaque psoriasis. The goal is to see if AUR101 can reduce symptoms by targeting inflammation and slowing down skin cell growth.

Eligible Conditions
  • Plaque Psoriasis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from day 1 through follow up visit at week 14
This trial's timeline: 3 weeks for screening, Varies for treatment, and from day 1 through follow up visit at week 14 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Proportion of patients achieving PASI 75 response (i.e. 75 percent reduction from baseline PASI [Psoriasis Area and Severity Index] score) at the end of week 12.
Secondary study objectives
Changes in Blood Pressure
Changes in CBC (Complete Blood Count)
Changes in Liver Function Tests
+15 more
Other study objectives
Metabolite of AUR101 identification from plasma collected at week 4
Metabolite of AUR101 identification from urine collected at week 4
Metabolite of AUR101 quantification from plasma collected at week 4
+8 more

Side effects data

From 2021 Phase 2 trial • 90 Patients • NCT04207801
7%
Pruritus
100%
80%
60%
40%
20%
0%
Study treatment Arm
Arm-1
Arm-2
Arm-3

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: AUR101 400 mg PO QDExperimental Treatment1 Intervention
Patients will receive AUR101 / placebo in double blind, double dummy manner
Group II: AUR101 400 mg PO BIDExperimental Treatment1 Intervention
Patients will receive AUR101 / placebo in double blind, double dummy manner
Group III: AUR101 200 mg PO BIDExperimental Treatment1 Intervention
Patients will receive AUR101 / placebo in double blind, double dummy manner
Group IV: PlaceboPlacebo Group1 Intervention
Patients will receive AUR101 / placebo in double blind, double dummy manner
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
AUR101
2020
Completed Phase 2
~240

Find a Location

Who is running the clinical trial?

Aurigene Discovery Technologies LimitedLead Sponsor
6 Previous Clinical Trials
330 Total Patients Enrolled
Divyesh Mandavia, MDStudy DirectorAurigene Discovery Technologies Limited
~31 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top