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Device

Active rTMS for Depression

N/A
Waitlist Available
Led By Jonathan Downar
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment
Awards & highlights
No Placebo-Only Group

Summary

This trial will test if additional sessions of transcranial magnetic stimulation can help people with major depression achieve remission.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Beck Depression Inventory-II (BDI-II) (score 0-63, higher = more severe)
Secondary study objectives
Hamilton Depression Rating Scale 17-items (HDRS17) (score 0-52, higher = more severe)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Active rTMSExperimental Treatment1 Intervention
Treatment will be delivered daily (weekdays) rTMS treatments, for up to 10 daily sessions and up to 75 sessions in total.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Repetitive Transcranial Magnetic Stimulation (rTMS)
2019
Completed Phase 2
~780

Find a Location

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,520 Previous Clinical Trials
503,194 Total Patients Enrolled
55 Trials studying Depression
11,297 Patients Enrolled for Depression
Centre for Addiction and Mental HealthOTHER
368 Previous Clinical Trials
82,986 Total Patients Enrolled
89 Trials studying Depression
18,156 Patients Enrolled for Depression
Jonathan DownarPrincipal InvestigatorUniversity Health Network, Toronto
~8 spots leftby Nov 2025
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