Trials in Chicago, Illinois
Here are the top 10 medical studies for glioblastoma in Chicago, Illinois
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Phase 3 Trials
Alkylating agents
Lomustine + Standard Therapy for Glioblastoma
Recruiting2 awardsPhase 3
Aurora, Illinois
This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.
Chemotherapy
Ultrasound-Assisted Chemotherapy for Glioblastoma
Recruiting2 awardsPhase 3
Chicago, Illinois
This trial tests a new method to treat recurrent brain cancer using an ultrasound device called SonoCloud-9. The device helps open the brain's protective barrier so that more of the chemotherapy drug carboplatin can reach the tumor. The goal is to see if this combination makes the treatment more effective. Carboplatin has been used in various studies for treating high-grade gliomas and glioblastomas, often showing modest efficacy due to low tissue concentration when delivered intravenously.
Alkylating agents
Multiple Therapies for Glioblastoma
Recruiting1 awardPhase 2 & 3
Milwaukee, Wisconsin
This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.
Intraoperative Radiotherapy for Glioblastoma
Recruiting2 awardsPhase 3
Maywood, Illinois
This trial is testing if adding intraoperative radiotherapy (IORT) to standard radiochemotherapy can improve the median progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM).
Trials With No Placebo
Monoclonal Antibodies
Tocilizumab + Atezolizumab + Radiation Therapy for Glioblastoma
Recruiting1 awardPhase 2
Chicago, Illinois
This trial tests a combination of tocilizumab, atezolizumab, and precise radiation therapy in patients with recurrent glioblastoma. Tocilizumab reduces inflammation, atezolizumab boosts the immune system, and the radiation targets the tumor. The goal is to make the tumor more responsive to treatment and improve patient outcomes.
Anti-tumor antibiotic
Ultrasound-assisted Chemotherapy for Glioblastoma
Recruiting3 awardsPhase 1 & 2
Chicago, Illinois
This trial will test a new way of giving the chemotherapy drug paclitaxel to people with glioblastoma that has come back after surgery. In this trial, they will give the drug through a device that uses ultrasound to open the blood brain barrier for a short time so that the drug can get into the brain.
Virus Therapy
ST101 for Advanced Cancer
Recruiting1 awardPhase 1 & 2
Warrenville, Illinois
This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.
Device
Optune + Radiation & Chemotherapy for Brain Cancer
Recruiting1 award12 criteria
Chicago, Illinois
This trial is testing a new treatment for brain cancer that combines Optune with radiation and chemotherapy. The goal is to see if this new combination is more effective and has fewer side effects than current treatments.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' ā so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back ā in general, verified trials respond to patients within a few days.