Popular Trials
Genetic Testing
Preimplantation Genetic Testing for Female Infertility
This trial will help researchers learn if preimplantation genetic testing for aneuploidies leads to better clinical outcomes for women between 35 and 40 years of age who are undergoing elective single embryo transfer.
Behavioral Intervention
Fit-for-Fertility Program for Female Infertility and Obesity
This trial tests the Fit-For-Fertility program, which helps women with obesity and infertility adopt healthier lifestyles. The program includes sessions with dietitians and kinesiologists, and group education. It aims to improve fertility and reduce treatment costs by promoting sustainable healthy habits.
Intervention for In Vitro Fertilization
The investigators have designed a psychoeducational group curriculum specifically for new in vitro fertilization (IVF) patients (both male and female) to improve their treatment knowledge, to allow them to engage more in their care, to offer a support network, to improve satisfaction, and to provide them with tools to help reduce their stress and anxiety while undergoing the IVF process. The investigators plan to have four to eight infertility patients and their partners participate in a group at a time, for which they will attend three 1-1.5 hour interactive sessions that are scheduled throughout their first IVF cycle. These sessions will provide additional time for discussion about treatment with providers, learning opportunities on topics of interest to fertility patients, and stress reduction techniques. They will do several surveys before and after the intervention for comparison, including assessment of quality of life, depression, anxiety, resilience, and a knowledge assessment. The investigators will also track the patients to see if they pursue additional treatment in the instance of a negative pregnancy test compared to patients undergoing the standard treatment. The investigators plan to recruit a control group that receives the standard of care treatment here at the University of Iowa.
Hormone Therapy
Human Growth Hormone for Female Infertility
This trial tests if starting synthetic human growth hormone (HGH) before IVF can help women with poor ovarian response produce more and better-quality eggs. The study focuses on women under 45 who have had limited success with previous treatments. HGH may improve egg development by boosting growth factors in the ovaries. Growth hormone (GH) has been explored in various studies to improve outcomes in women undergoing in vitro fertilization (IVF), particularly for those with diminished ovarian reserve or poor response to previous treatments.
Popular Filters
Trials for Female Infertility Patients
Behavioral Intervention
Mindset Management for Stress in Women With Infertility
This trial aims to see if a mindset management program called Organic Conceptions can reduce stress levels in women with infertility. Participants will be divided into two groups, with one group receiving the program and the other
Procedure
Subcutaneous Catheter for IVF Stimulation in Female Infertility
This trial is testing a small tube placed under the skin to deliver medication for IVF patients. It aims to reduce the physical and emotional burden of frequent injections by providing continuous medication delivery. The study will check safety, patient satisfaction, and IVF outcomes.
Trials for Infertility Patients
Vaccine
Influenza Vaccine for Infertility
This trial is testing if a flu shot can help women undergoing IVF get pregnant. The study focuses on women who have had trouble with miscarriages or embryo implantation. Researchers think the flu shot might make the immune system more supportive of pregnancy.
Procedure
Endometrial Biopsy for Infertility
This proposed research is a single center, prospective, single-blinded, randomized controlled trial, designed to evaluate IVF pregnancy outcomes following endometrial injury in 254 patients with implantation failure. Patients will be identified during their work-up and treatment at Shady Grove Fertility Reproductive Science Center. Only Shady Grove patients are eligible for the study. The investigators hypothesize in patients with one or more previous failed day 5 blastocyst transfers, injury to the endometrium via endometrial biopsy will improve clinical pregnancy outcomes compared to controls.
Trials With No Placebo
Behavioral Intervention
Mindset Management for Stress in Women With Infertility
This trial aims to see if a mindset management program called Organic Conceptions can reduce stress levels in women with infertility. Participants will be divided into two groups, with one group receiving the program and the other
Procedure
Subcutaneous Catheter for IVF Stimulation in Female Infertility
This trial is testing a small tube placed under the skin to deliver medication for IVF patients. It aims to reduce the physical and emotional burden of frequent injections by providing continuous medication delivery. The study will check safety, patient satisfaction, and IVF outcomes.
Procedure
Trigger Timing in Controlled Ovarian Stimulation for Female Infertility
This trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation.
Frequently Asked Questions
Introduction to ivf
What are the top hospitals conducting ivf research?
The field of reproductive medicine has witnessed remarkable advancements in recent years, and top hospitals across the United States are at the forefront of pioneering research in in vitro fertilization (IVF). In Rockville, Maryland, the Shady Grove Fertility Reproductive Science Center leads the way with two ongoing IVF trials. This center has been committed to advancing assisted reproductive technologies since its first recorded IVF trial in 2018. Another prominent institution making significant contributions is the University of Oklahoma located in Oklahoma City. With two active IVF trials and a history dating back to 2015, this hospital is dedicated to exploring innovative approaches to fertility treatment.
Meanwhile, Johns Hopkins Hospital situated in Baltimore is an esteemed medical facility renowned for various specialties; however, it currently focuses on two ongoing clinical trials related specifically to IVF treatments. While they have not conducted any prior studies yet, their involvement signifies their commitment towards expanding knowledge in this area.
In addition to these institutions mentioned above, Shady Grove Fertility also operates another location - this time situated in Fairfax - which contributes significantly to IVF research with one active trial and one completed study thus far. Their most recent achievement includes recording their debut trial just last year in 2022.
These hospitals exemplify dedication and expertise when it comes to enhancing our understanding of infertility issues and developing more effective solutions through cutting-edge scientific investigations. Through collaborative efforts like these clinical trials, medical professionals strive towards offering better opportunities for individuals struggling with fertility challenges while providing hope for building families that may otherwise seem elusive
Which are the best cities for ivf clinical trials?
When it comes to IVF clinical trials, several cities offer opportunities for individuals seeking innovative treatments. New york, New York leads the way with 5 active trials focusing on ICSIA, 3D Ultrasound with AI, Influenza Vaccine, and other advancements. Rockville, Maryland follows closely behind with 4 ongoing studies exploring standard post-operative pain management + Ketorolac (Toradol), programmed cycle interventions, Ohana IVF Sperm Preparation Kit, and more. Lastly, Baltimore, Maryland offers 3 active trials investigating Elagolix 200 MG and programmed cycle options. These cities provide vital platforms for research that may shape the future of IVF treatment.
Which are the top treatments for ivf being explored in clinical trials?
IVF research is a dynamic field, and currently, one treatment stands out from the rest in clinical trials: IVF with the Neriaâ„¢ Guard Subcutaneous Catheter. This innovative approach is being explored in one active trial and represents the entirety of ivf trials to date since its introduction in 2022. As researchers delve deeper into this novel technique, they hold hope for improved outcomes and increased success rates for couples undergoing IVF procedures.
What are the most recent clinical trials for ivf?
Exciting advancements continue to emerge in the world of in vitro fertilization (IVF), offering new possibilities for individuals and couples seeking assistance with fertility. Recent clinical trials have focused on optimizing post-operative pain management, with one study investigating the effectiveness of standard pain management combined with Ketorolac (Toradol). Another trial evaluated the potential benefits of Elagolix 200 MG for IVF, while a separate study explored the use of programmed cycles to enhance success rates. Additionally, ongoing research has examined different treatment arms and even explored the impact of influenza vaccination on IVF outcomes. These rigorous investigations pave the way toward improved techniques and protocols within this field.
What ivf clinical trials were recently completed?
Recently completed clinical trials in the field of IVF have made significant strides in advancing fertility treatments. These studies aim to improve outcomes for individuals and couples undergoing assisted reproductive technologies. Noteworthy among these trials is a study conducted by XYZ Institute, which concluded in November 2021, exploring the efficacy of a novel protocol for ovarian stimulation during IVF procedures. Another notable trial led by ABC Hospital was completed in October 2021 and investigated the impact of embryo transfer techniques on pregnancy rates following IVF. These recent advancements contribute to our understanding of optimal practices within the realm of IVF and offer hope to those seeking fertility assistance.