Popular Trials
Opioid Analgesic
Buprenorphine for Pain relief
Recruiting2 awards6 criteria
Los Angeles, California
The aim of this study is to examine the effects of opioid analgesics on acute pain in participants maintained on buprenorphine+naloxone (Suboxone) for opioid use disorders. Seven medication conditions will be tested in a cold pressor test (CPT) paradigm.
Opioid Analgesic
Buprenorphine for Chronic Pain
Recruiting3 awardsPhase 2
New York, New York
The purpose of this study is to develop and pilot test clinical guidelines for the use of buprenorphine for the treatment chronic pain among patients with substance abuse histories. Buprenorphine, an opioid medication, holds promise as a treatment of chronic pain because, compared to most other opioid analgesics, it has a high safety profile, a low level of physical dependence, and mild withdrawal symptoms on cessation. Moreover there are promising reports from Europe of its use as a skin patch to treat chronic pain as well as clinical reports in the U.S. that it may be effective when used sublingually (placed under the tongue). This study will test the sublingual formulation.
Opioid Partial Agonist
Buprenorphine for Opioid Use Disorder
Recruiting3 awardsPhase 2
Oakland, California
This trial will recruit patients with opioid use disorder who present to the emergency department, and compare the effectiveness of two different medication treatments for engaging them in formal addiction treatment 7 days later.
Popular Filters
Phase 3 Trials
Opioid Partial Agonist
Extended Release Buprenorphine for Opioid Use Disorder
Recruiting1 awardPhase 2 & 3
New Haven, Connecticut
This trial is testing whether a 28-day formulation of extended-release buprenorphine is more effective than usual treatment for patients with a moderate or severe opioid use disorder who are seen by an addiction consultation service and agree to start a medication for OUD.
Opioid Agonist
Buprenorphine for Opioid Addiction during Pregnancy
Recruiting2 awardsPhase 3
Jacksonville, Florida
This trial is testing whether an extended-release form of buprenorphine is as effective as the standard form in treating pregnant women with opioid use disorder, with the goal of improving outcomes for mother and child.
Trials With No Placebo
Opioid Agonist
Buprenorphine/naloxone for Opioid Use Disorder
Recruiting3 awards6 criteria
Baltimore, Maryland
This trial tests a new device called BupreCare that helps people with opioid addiction take their medication correctly. The device locks the pills and only gives the right amount at the right time, while also tracking when the medication is taken. This helps doctors monitor their patients and improve treatment outcomes. Buprenorphine is a medication approved in the United States for the treatment of opioid dependence, offering a safe and effective alternative for individuals with opioid addiction.
Opioid Analgesic
Buprenorphine +1 More for Pain
Recruiting3 awardsPhase 2
Oakland, California
This study evaluates intravenous (IV) buprenorphine versus IV morphine for the management of severe, acute pain among emergency department (ED) patients. ED patients with severe pain will be randomized in equal proportion to receive IV buprenorphine or IV morphine.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.