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Salt pills for High Blood Pressure

Phase < 1

Waitlist Available

Research Sponsored by Augusta University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 weeks

Summary

This trial tests if reducing salt intake through nutritional counseling can improve gut health and lower blood pressure in adults aged 18-50 with normal or slightly high blood pressure. Participants will receive different levels of salt to see how it affects their health.

Eligible Conditions

High Blood Pressure

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Gut microbiota diversity using 16s rRNA Sequencing

Secondary study objectives

Gut intestine barrier integrity measured by non-invasive biomarkers

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: High sodiumExperimental Treatment1 Intervention

Subjects will be counseled to consume a diet with 2,300 mg/d sodium which they will supplement with pills containing salt to achieve an intake of 4,300 mg/d sodium for 4 weeks.

Group II: PlaceboPlacebo Group1 Intervention

Subjects will be counseled to consume a diet with 2,300 mg/d sodium and will supplement with taking placebo pills for 4 weeks.

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