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Retinoid

S6G5T-3 for Acne

Phase 1
Waitlist Available
Research Sponsored by Sol-Gel Technologies, Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 14 days
Awards & highlights
All Individual Drugs Already Approved
Approved for 5 Other Conditions
No Placebo-Only Group

Summary

This trial tests a new acne cream called S6G5T-3 to see how much of it gets into the body compared to an existing cream. It involves people aged 12 and older who have acne.

Eligible Conditions
  • Acne

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~14 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 14 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Pharmacokinetics of S6G5T-3 as measured by the maximum observed plasma concentration

Side effects data

From 2019 Phase 3 trial • 434 Patients • NCT03761810
10%
Application site pain
4%
Application site dryness
3%
Application site erythema
3%
Application site exfoliation
2%
Application site pruritus
2%
Application site dermatitis
1%
Application site photosensitivity
1%
Nasopharyngitis
100%
80%
60%
40%
20%
0%
Study treatment Arm
S6G5T-3
S6G5T-8 Vehicle Cream

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: S6G5T-3Experimental Treatment1 Intervention
topical cream
Group II: Retin-A® 0.1% CreamActive Control1 Intervention
topical cream
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
S6G5T-3
2018
Completed Phase 3
~1650

Find a Location

Who is running the clinical trial?

Sol-Gel Technologies, Ltd.Lead Sponsor
14 Previous Clinical Trials
4,201 Total Patients Enrolled
~10 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
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