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Polyphenolic Compounds

Purple Carrots for Diabetes

Phase 1
Waitlist Available
Research Sponsored by University of Guelph
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Summary

The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods. Diets of human subjects will be modified to allow consumption of 200-300 g of raw carrots or cooked potatoes. Participants will be randomized to consume either orange or purple carrots, or white or purple potatoes. They will consume these diets for 12 weeks and bioavailability of polyphenolics will be examined as well as anthropometry and blood biochemistry for changes in risk factors associated with cardiovascular disease.

Eligible Conditions
  • Diabetes
  • Inflammation
  • Obesity
  • High Blood Pressure
  • High Cholesterol

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Cholesterol
Secondary study objectives
blood and urinary polyphenol metabolites
blood pressure
body composition
+2 more

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Purple PotatoExperimental Treatment1 Intervention
Participants will consume 300-500 g of cooked purple potato per day
Group II: Purple CarrotsExperimental Treatment1 Intervention
Participants will consume 200-300 g raw purple carrots instead of orange carrots in the control arm
Group III: Orange carrotsPlacebo Group1 Intervention
Participants will consume 200-300 g typical varieties of orange carrots during the intervention
Group IV: White potatoPlacebo Group1 Intervention
Participants will consume 300-500 g of cooked white potatoes per day

Find a Location

Who is running the clinical trial?

Ontario Ministry of Agriculture, Food and Rural AffairsOTHER_GOV
8 Previous Clinical Trials
329 Total Patients Enrolled
1 Trials studying Diabetes
14 Patients Enrolled for Diabetes
University of GuelphLead Sponsor
81 Previous Clinical Trials
14,888 Total Patients Enrolled
~4 spots leftby Sep 2025
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