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LY3462817 (SC) for Healthy Subjects

Phase 1
Waitlist Available
Research Sponsored by Eli Lilly and Company
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up predose on day 1 through day 85

Summary

This trial tests a new drug, LY3462817, to see if it is safe and how the body handles it. Healthy Japanese and non-Japanese people will participate. Researchers will measure how fast the drug gets into the blood and how long it takes to leave.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~predose on day 1 through day 85
This trial's timeline: 3 weeks for screening, Varies for treatment, and predose on day 1 through day 85 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration
Secondary study objectives
PK: Maximum Concentration (Cmax) of LY3462817
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of LY3462817

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: LY3462817 - SCExperimental Treatment1 Intervention
LY3462817 administered subcutaneously (SC)
Group II: LY3462817 - IVExperimental Treatment1 Intervention
LY3462817 administered intravenously (IV)
Group III: Placebo - IVPlacebo Group1 Intervention
Placebo administered IV
Group IV: Placebo - SCPlacebo Group1 Intervention
Placebo administered SC
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
LY3462817 (IV)
2022
Completed Phase 1
~40
LY3462817 (SC)
2022
Completed Phase 1
~40

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Eli Lilly and CompanyLead Sponsor
2,667 Previous Clinical Trials
3,228,444 Total Patients Enrolled
Study DirectorEli Lilly and Company
1,383 Previous Clinical Trials
426,108 Total Patients Enrolled
~10 spots leftby Nov 2025
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