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Insulin

Intranasal insulin for Cardiac Arrest

Phase 1
Waitlist Available
Led By Robert Silbergleit, MD
Research Sponsored by Robert Silbergleit
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 4 hours after drug administration
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing insulin nose drops in healthy people to find the safest dose. The goal is to see if this method can protect the brain after a heart attack.

Eligible Conditions
  • Cardiac Arrest
  • Healthy Subjects

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 4 hours after drug administration
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 4 hours after drug administration for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Severe Hypoglycemia as defined by blood glucose < 45 milligrams per deciliter (mg/dL)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Intranasal insulinExperimental Treatment1 Intervention
A total of 11 possible doses will be tested, ranging from 0 to 1000 U insulin.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Intranasal insulin
2006
Completed Phase 2
~190

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Robert SilbergleitLead Sponsor
1 Previous Clinical Trials
1,023 Total Patients Enrolled
American Heart AssociationOTHER
344 Previous Clinical Trials
4,971,381 Total Patients Enrolled
7 Trials studying Cardiac Arrest
7,004 Patients Enrolled for Cardiac Arrest
Robert Silbergleit, MDPrincipal InvestigatorUniversity of Michigan
3 Previous Clinical Trials
2,012 Total Patients Enrolled
~6 spots leftby Nov 2025
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