← Back to Search

Behavioural Intervention

Non-Invasive Vibration Therapy for Parkinson's Disease

N/A
Waitlist Available
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 1 week, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months
Awards & highlights
No Placebo-Only Group

Summary

This trial will test a non-invasive device to reduce Parkinson's symptoms. Patients will be monitored for two years to see if the device works.

Who is the study for?
This trial is for people aged 35-90 with advanced Parkinson's Disease (stages 2 to 4), who are comfortable with technology and can manage without certain brain function medications during EEG recordings. They must not be pregnant, involved in other trials recently, have a history of significant brain surgery or severe psychiatric issues, or substance abuse problems.
What is being tested?
The study tests Vibrotactile Coordinated Reset stimulation using the vibrotactile axon Glove on Parkinson's symptoms. It offers a non-invasive treatment alternative to levodopa or deep brain stimulation and monitors patients over two years.
What are the potential side effects?
Potential side effects aren't specified but as vCR is non-invasive and doesn't involve drugs, it may be associated with less risk than medication or surgical options. However, discomfort from glove use or skin irritation could occur.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 1 week, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 week, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Movement Disorders Society Unified Parkinson's Disease Rating Scale Part 3 (MDS-UPDRS III) off medication
Secondary study objectives
Communicative Participation Item Bank (CPIB; Short Form)
Freezing of Gait Questionnaire (FOG)
Levodopa equivalent daily dose (LEDD)
+9 more
Other study objectives
Quantitative Digitography Repetitive Alternating Finger Task (QDG-RAFT)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Vibrotactile Coordinated Reset (vCR)Experimental Treatment1 Intervention
Vibrotactile Coordinated Reset delivers vibratory stimulation to the fingertips of each hand. A specific pattern of vibration to each fingertip is delivered which theoretically disrupts abnormal synchrony in the brain.

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,468 Previous Clinical Trials
17,496,247 Total Patients Enrolled

Media Library

Vibrotactile Coordinated Reset (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05504902 — N/A
Parkinson's Disease Research Study Groups: Vibrotactile Coordinated Reset (vCR)
Parkinson's Disease Clinical Trial 2023: Vibrotactile Coordinated Reset Highlights & Side Effects. Trial Name: NCT05504902 — N/A
Vibrotactile Coordinated Reset (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05504902 — N/A
Parkinson's Disease Patient Testimony for trial: Trial Name: NCT05504902 — N/A
~21 spots leftby Nov 2026