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Behavioural Intervention

Strength Training for Head and Neck Cancer Survivors (LIFTING2 Trial)

Phase 2
Waitlist Available
Led By Kerry Courneya
Research Sponsored by University of Alberta
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, postintervention (12 weeks), and monitored throughout 12 week study period
Awards & highlights

Summary

"This trial will examine whether heavy lifting strength training can help improve side effects in head and neck cancer survivors, such as loss of muscle strength and fatigue, which impact their quality of life and ability to return

Who is the study for?
This trial is for head and neck cancer survivors who have finished their treatment. It's designed to see if heavy lifting strength training can help with muscle strength, physical function, fatigue, and swallowing issues that affect life quality.
What is being tested?
The LIFTING 2 trial is testing the benefits of a heavy lifting strength training program compared to no exercise at all in people who've survived head and neck cancer. The goal is to improve their muscular strength and overall well-being.
What are the potential side effects?
Since this study involves physical exercise, potential side effects may include muscle soreness or injury. However, these are generally mild and manageable with proper supervision.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, postintervention (12 weeks), and monitored throughout 12 week study period
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, postintervention (12 weeks), and monitored throughout 12 week study period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Adherence to a heavy lifting strength training program
Completion of maximal strength testing
Followup assessment rate
+2 more
Secondary study objectives
Body composition
Cancer Specific Quality of Life
Fear of Cancer Recurrence
+10 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Exercise GroupExperimental Treatment1 Intervention
The exercise intervention will consist of 24 supervised, heavy lifting strength training exercise sessions over a 12 week period. The exercise frequency will be two times per week. Main exercises will consist of barbell back squat, bench press, and dead lift.
Group II: Usual Care GroupActive Control1 Intervention
Participants randomized to the usual care group will be asked to continue will their typical daily routine during the 12 week study period, and not begin any new exercise program to increase their exercise levels from baseline. They will not receive any information or education regarding exercise. After the postintervention assessments, participants in the usual care group will be offered a 4-week introduction to heavy lifting strength training program and/or referred to a community-based exercise program

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Who is running the clinical trial?

University of AlbertaLead Sponsor
913 Previous Clinical Trials
390,373 Total Patients Enrolled
Kerry CourneyaPrincipal InvestigatorUniversity of Alberta
~40 spots leftby Jan 2026
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