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Immunomodulator

ABX196 for Hepatocellular Carcinoma

Phase 1 & 2
Recruiting
Led By Darren SIGAL, MD
Research Sponsored by Abivax S.A.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 1 year
Awards & highlights

Summary

This trial is testing a new drug, ABX196, to see if it is safe and effective in treating hepatocellular carcinoma when used with nivolumab.

Eligible Conditions
  • Hepatocellular Carcinoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incidence of adverse events (AEs)
Secondary study objectives
Objective Response Rate (ORR)

Trial Design

1Treatment groups
Experimental Treatment
Group I: ABX196Experimental Treatment1 Intervention
IM injection of 0.1, 0.2, and 0.4 µg of ABX196

Find a Location

Who is running the clinical trial?

Abivax S.A.Lead Sponsor
21 Previous Clinical Trials
4,399 Total Patients Enrolled
C3 Research AssociatesUNKNOWN
2 Previous Clinical Trials
111 Total Patients Enrolled
Darren SIGAL, MDPrincipal InvestigatorScripps Clinic/Scripps MD Anderson Cancer Center
~8 spots leftby Sep 2025