← Back to Search

Prodrug

TF0023 for COVID-19

Phase 2
Waitlist Available
Research Sponsored by Techfields Inc
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 28 days
Awards & highlights
No Placebo-Only Group

Summary

This trial tests a new spray medicine, AMP5A, for hospitalized adults with severe COVID-19 lung issues. The spray aims to reduce inflammation and improve breathing.

Eligible Conditions
  • COVID-19

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~28 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 28 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Percentage of patients able to maintain peripheral capillary oxygen saturation (SpO2) of >93% without oxygen support at Day 15.
Secondary study objectives
All-cause mortality
Changes of chest x-ray, and computerized tomography (CT) scan
Changes of clinical status (9-point ordinal scale)
+7 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

4Treatment groups
Experimental Treatment
Group I: Low Dose of Active DrugExperimental Treatment1 Intervention
80 patients will be randomly assigned to low dose, take active drug BID.
Group II: Low Dose Placebo ControlExperimental Treatment1 Intervention
80 patients will be randomly assigned to Low dose placebo, take the placebo BID.
Group III: High Dose of Active DrugExperimental Treatment1 Intervention
160 patients will be randomly assigned to high dose, take the active drug BID.
Group IV: High Dose Placebo ControlExperimental Treatment1 Intervention
80 will be randomly assigned to high dose placebo, take the placebo BID.

Find a Location

Who is running the clinical trial?

Techfields IncLead Sponsor
1 Previous Clinical Trials
225 Total Patients Enrolled
Chongxi Yu, Ph.DStudy ChairTechfields Inc
1 Previous Clinical Trials
225 Total Patients Enrolled
~6 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top