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CAR T-cell Therapy

Cohort 4 for Multiple Myeloma

Phase 1 & 2
Waitlist Available
Led By John A Lust, MD, PhD
Research Sponsored by Senesco Technologies, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 3 and 6, and monthly during a 24-week follow-up period
Awards & highlights
No Placebo-Only Group

Summary

The purpose of this study is to determine how well SNS01-T is tolerated by relapsed or refractory multiple myeloma, B cell lymphoma or plasma cell leukemia patients when given by intravenous infusion at various doses.

Eligible Conditions
  • Multiple Myeloma
  • Mantle Cell Lymphoma
  • Lymphoma
  • Leukemia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 3 and 6, and monthly during a 24-week follow-up period
This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 3 and 6, and monthly during a 24-week follow-up period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Safety and tolerability
Secondary study objectives
Explore tumor response
Profile of pharmacokinetics

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

4Treatment groups
Experimental Treatment
Group I: Cohort 4Experimental Treatment1 Intervention
0.375 mg/kg
Group II: Cohort 3Experimental Treatment1 Intervention
0.2 mg/kg
Group III: Cohort 2Experimental Treatment1 Intervention
0.05 mg/kg
Group IV: Cohort 1Experimental Treatment1 Intervention
0.0125 mg/kg

Find a Location

Who is running the clinical trial?

Senesco Technologies, Inc.Lead Sponsor
John A Lust, MD, PhDPrincipal InvestigatorMayo Clinic
1 Previous Clinical Trials
60 Total Patients Enrolled
~1 spots leftby Nov 2025
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