← Back to Search

Tart Cherry Juice for Breast Cancer

Phase 2

Recruiting

Led By Eve Rodler, MD

Research Sponsored by Eve Rodler

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Histologically confirmed invasive breast or ovarian cancer (Stage I, II, III, or IV) as per AJCC 8th Edition, 2018 Staging Criteria

Age ≥ 18 years old at the time of consent

Must not have

Active or history of peripheral neuropathy or associated chronic diseases

Currently taking anticoagulant medication

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 1 year.

Awards & highlights

No Placebo-Only Group

Summary

This trial is looking at whether tart cherry juice can help prevent nerve damage caused by certain chemotherapy drugs in breast and ovarian cancer patients. Participants will be randomly assigned to receive either a high dose or low dose

Who is the study for?

This trial is for breast and ovarian cancer patients about to undergo paclitaxel chemotherapy. Participants should not have any health conditions that exclude them from the study, but specific exclusion criteria are not listed here.

What is being tested?

The study tests if tart cherry juice can prevent neuropathy caused by paclitaxel in two doses: high (Arm 1) and low (Arm 2). Patients will be randomly assigned to either group in equal numbers.

What are the potential side effects?

While the side effects of tart cherry juice aren't specified, it's generally considered safe with possible mild digestive discomfort as a common side effect.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My breast or ovarian cancer is confirmed and staged.

Select...

I am 18 years old or older.

Select...

I am fully active or can carry out light work.

Select...

I am scheduled to receive weekly paclitaxel for 12 weeks.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have or had nerve damage or diseases related to it.

Select...

I am currently on blood thinner medication.

Select...

I am currently taking certain supplements or medications.

Select...

I cannot swallow liquids.

Select...

I have taken specific medications before.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 1 year.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 1 year.

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 year. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Efficacy of tart cherry juice supplementation in the prevention of paclitaxel-induced peripheral neuropathy (PIPN) in breast and ovarian cancer patients undergoing treatment with paclitaxel-based chemotherapy.

Secondary study objectives

Assess the impact of tart cherry juice on dose delivery of taxane chemotherapy.

Compare the effectiveness of high- dose and low-dose tart cherry juice supplement in reducing the severity of PIPN in breast and ovarian cancer patients undergoing treatment with paclitaxel-based chemotherapy.

Safety profile of daily intake of high-dose and low-dose tart cherry juice.

+1 more