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EKSO+ES for Spinal Cord Injury (ESL-SCI Trial)

Phase 1 & 2
Waitlist Available
Led By Ashraf S Gorgey, PhD
Research Sponsored by McGuire Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights
No Placebo-Only Group

Summary

This trial will test the effects of epidural stimulation (ES) on motor control recovery in veterans with spinal cord injuries (SCI). The intervention will be accompanied with the use of a powered exoskeleton (EKSO) for 6 months to facilitate standing and to produce step-like movement.

Eligible Conditions
  • Spinal Cord Injury

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Six minute-walk and 10-meter walk distance Tests
Surface electromyography of 6 different muscle groups
Secondary study objectives
Body composition assessment of fat mass and fat-free mass using dual energy x-ray absorptiometry (DXA)
Oxygen uptake using Portable Indirect Calorimetry
Systolic and Diastolic Blood Pressure

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: EKSO+ESExperimental Treatment1 Intervention
6 months of exoskeleton training with spinal cord epidural stimulation.

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Who is running the clinical trial?

McGuire Research InstituteLead Sponsor
9 Previous Clinical Trials
376 Total Patients Enrolled
Ashraf S Gorgey, PhDPrincipal InvestigatorHunter Holmes McGuire VA Medical Center
1 Previous Clinical Trials
20 Total Patients Enrolled
~1 spots leftby Nov 2025
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