← Back to Search

Opioid Analgesic

hydromorphone HCI for Pain relief

N/A
Waitlist Available
Led By Walter Ling, MD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 testing sessions over 12 weeks
Awards & highlights
Approved for 10 Other Conditions
All Individual Drugs Already Approved

Summary

The aim of this study is to examine the effects of opioid analgesics on acute pain in participants maintained on buprenorphine+naloxone (Suboxone) for opioid use disorders. Seven medication conditions will be tested in a cold pressor test (CPT) paradigm.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 testing sessions over 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 testing sessions over 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Pain detection
Pain tolerance
Secondary study objectives
Pupillometry results

Awards & Highlights

Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

7Treatment groups
Experimental Treatment
Placebo Group
Group I: oxycodoneExperimental Treatment1 Intervention
10 mg single dose
Group II: morphine sulfateExperimental Treatment1 Intervention
30mg, single dose,
Group III: hydromorphone HCIExperimental Treatment1 Intervention
4mg single dose
Group IV: hydrocodoneExperimental Treatment1 Intervention
10mg single dose
Group V: buprenorphineExperimental Treatment1 Intervention
4 mg single dose
Group VI: oral tablet placeboPlacebo Group4 Interventions
single dose
Group VII: sublingual tablet placeboPlacebo Group1 Intervention
single dose

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,561 Previous Clinical Trials
10,258,994 Total Patients Enrolled
Indivior Inc.Industry Sponsor
55 Previous Clinical Trials
11,344 Total Patients Enrolled
Walter Ling, MDPrincipal InvestigatorUniversity of California, Los Angeles
1 Previous Clinical Trials
360 Total Patients Enrolled
~1 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top