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IMB-1018972 for Hypertrophic Cardiomyopathy (IMPROVE-HCM Trial)

Phase 2
Waitlist Available
Research Sponsored by Imbria Pharmaceuticals, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years

Summary

This trial is testing a new drug called IMB-1018972 to see if it is safe and effective. The drug is for patients with a specific heart condition called non-obstructive hypertrophic cardiomyopathy (HCM). It aims to help their hearts work better and reduce their symptoms.

Eligible Conditions
  • Hypertrophic Cardiomyopathy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: IMB-1018972 200mgExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
IMB-1018972
2021
Completed Phase 2
~130

Find a Location

Who is running the clinical trial?

Imbria Pharmaceuticals, Inc.Lead Sponsor
3 Previous Clinical Trials
748 Total Patients Enrolled
Paul Chamberlin, MDStudy DirectorImbria Pharmaceuticals, Inc.
6 Previous Clinical Trials
1,887 Total Patients Enrolled
Medical MonitorStudy ChairImbria Pharmaceuticals, Inc.
1,674 Previous Clinical Trials
988,392 Total Patients Enrolled
~15 spots leftby Nov 2025
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