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Antibiotic

Doxycycline Hcl for COVID-19

Phase 1
Waitlist Available
Research Sponsored by ProgenaBiome
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months

Summary

In this trial patients will be treated with either a combination of therapies to treat COVID-19 or a placebo. Treatment will last 10 days, and patients will be followed for 6 months.

Eligible Conditions
  • COVID-19
  • Coronavirus
  • Coronavirus Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Efficacy of Treatment as measured by RT-PCR
Efficacy of Treatment as measured by Titer
Time to Non-Infectivity by RT-PCR
+2 more
Secondary study objectives
Safety of Treatment as Measured by C-Reactive Protein
Safety of Treatment as Measured by Complete Blood Count
Safety of Treatment as Measured by D-Dimer
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active ArmExperimental Treatment5 Interventions
Patients will be treated with a combination of Ivermectin, Doxycycline, Zinc, Vitamin D3 and Vitamin C
Group II: PlaceboPlacebo Group3 Interventions
Placebo and Vitamin D3, Vitamin C, and Zinc
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vitamin D3
2011
Completed Phase 4
~3590
Vitamin C
2017
Completed Phase 4
~18470
Ivermectin
2016
Completed Phase 4
~36480
Doxycycline Hcl
2011
Completed Phase 2
~60
Zinc
2005
Completed Phase 4
~16490

Find a Location

Who is running the clinical trial?

ProgenaBiomeLead Sponsor
45 Previous Clinical Trials
5,319 Total Patients Enrolled
6 Trials studying COVID-19
1,268 Patients Enrolled for COVID-19
Topelia TherapeuticsUNKNOWN
Sabine Hazan, MDStudy DirectorProgenaBiome
40 Previous Clinical Trials
4,998 Total Patients Enrolled
6 Trials studying COVID-19
1,268 Patients Enrolled for COVID-19
~6 spots leftby Nov 2025