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Morphine sulfate - Visit 1 for Pulmonary Arterial Hypertension

Phase 2

Waitlist Available

Led By John Granton, MD, FRCPC

Research Sponsored by John Granton

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the distance travelled during each 6 minute walk will be determined at completion of the 6-minute walk test. the distance travelled during the 6-minute walk test will be recorded within 1 and 7 days of each other.

Awards & highlights

All Individual Drugs Already Approved

Approved for 10 Other Conditions

No Placebo-Only Group

Summary

Despite advances in treatment and corresponding improvements in survival, patients with pulmonary arterial hypertension (PAH) remain highly symptomatic. In one survey of 315 patients with PAH, sixty-eight percent had moderate or severe dyspnea on exertion and 40% had a profound and clinically significant deficit in quality of life. Palliative care is being increasingly investigated in life-limiting cardiovascular diseases to alleviate symptoms. In PAH, its implementation is frequently delayed until end-of-life. Opioids are a common palliative care intervention, however the efficacy and safety of opioids for symptom relief in PAH has not been evaluated.

Eligible Conditions

Pulmonary Arterial Hypertension

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the distance travelled during each 6 minute walk will be determined at completion of the 6-minute walk test. the distance travelled during the 6-minute walk test will be recorded within 1 and 7 days of each other.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the distance travelled during each 6 minute walk will be determined at completion of the 6-minute walk test. the distance travelled during the 6-minute walk test will be recorded within 1 and 7 days of each other.

This trial's timeline: 3 weeks for screening, Varies for treatment, and the distance travelled during each 6 minute walk will be determined at completion of the 6-minute walk test. the distance travelled during the 6-minute walk test will be recorded within 1 and 7 days of each other. for reporting.