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Monoclonal Antibodies

Pre-PDT for Visual Acuity

Phase 4
Waitlist Available
Led By John Galic, MD
Research Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

The purpose of the investigators study is to look at the visual outcomes of Ranibizumab injections in combination with photodynamic therapy for the treatment of neovascular age-related macular degeneration.

Eligible Conditions
  • Visual Acuity
  • Age-Related Macular Degeneration

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

3Treatment groups
Active Control
Group I: Pre-PDTActive Control1 Intervention
Participants in this group will receive an intraocular Ranibizumab injection one week prior to the first PDT with verteporfin.
Group II: No PDTActive Control1 Intervention
Participants in this group will receive an intraocular Ranibizumab injection with no accompanying PDT with verteporfin.
Group III: Post-PDTActive Control1 Intervention
Participants in this group will receive an intraocular Ranibizumab injection one week post the first PDT with verteporfin.

Find a Location

Who is running the clinical trial?

McGill University Health Centre/Research Institute of the McGill University Health CentreLead Sponsor
461 Previous Clinical Trials
164,173 Total Patients Enrolled
John Galic, MDPrincipal InvestigatorMontreal Retina Institute
John Chen, MDPrincipal InvestigatorMontreal Retina Institute
~11 spots leftby Sep 2025