← Back to Search

Serotonin Modulator and Stimulator

Vortioxetine for Social Anxiety Disorder

Phase 4
Waitlist Available
Led By Michael R Liebowitz, M.D.
Research Sponsored by The Medical Research Network
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Summary

This trial is testing vortioxetine, a medication that may help adults who have both major depression and social anxiety. It works by balancing brain chemicals to improve mood and reduce anxiety. Vortioxetine is a new antidepressant approved by the US FDA for the treatment of major depressive disorder (MDD).

Eligible Conditions
  • Social Anxiety Disorder
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Clinical Global Impression of Improvement (CGI-I) Responder Rate

Side effects data

From 2019 Phase 4 trial • 1106 Patients • NCT02371980
26%
Nausea
8%
Headache
5%
Nasopharyngitis
5%
Dry mouth
100%
80%
60%
40%
20%
0%
Study treatment Arm
Open-label: Vortioxetine 10 mg
Double-blind: Placebo
Double-blind: Vortioxetine 5 mg
Double-blind: Vortioxetine 10 mg
Double-blind: Vortioxetine 20 mg

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: VortioxetineExperimental Treatment1 Intervention
Vortioxetine 10 to 20 mg PO QD for 12 weeks.
Group II: PlaceboPlacebo Group1 Intervention
Placebo PO QD for 12 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vortioxetine
FDA approved

Find a Location

Who is running the clinical trial?

The Medical Research NetworkLead Sponsor
5 Previous Clinical Trials
270 Total Patients Enrolled
Michael R Liebowitz, M.D.Principal InvestigatorThe Medical Research Network, LLC
~4 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top