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NA

New Treatment for Lung Cancer

N/A
Waitlist Available
Led By Dennis Wigle, MD, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patient must be > 18 years of age
No evidence of distant metastases
Must not have
Two or more GGO's or solid lesions suspicious for multifocal disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new treatment for lung cancer that has spread to other parts of the body.

Who is the study for?
This trial is for adults over 18 with multifocal lung adenocarcinoma, no distant metastases, and capable lungs for surgery. It's not for pregnant women or those who've had other cancers (except certain early-stage ones), prior chest radiation, chemotherapy, or lung cancer surgery.
What is being tested?
The study aims to evaluate the safety and outcomes of a combined treatment approach for patients with multifocal bronchioloalveolar carcinoma (BAC), a form of non-small cell lung cancer.
What are the potential side effects?
While specific side effects are not listed here, multimodality treatments can include surgery, radiation, and/or chemotherapy which may cause fatigue, pain at the surgical site, breathing difficulties post-surgery, skin irritation from radiation and various chemo-related side effects.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am older than 18 years.
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My cancer has not spread to distant parts of my body.
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My lung function tests show I can undergo lung surgery.
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I am a woman who can have children and have a negative pregnancy test.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have two or more lesions that may indicate my disease is in multiple places.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Overall Survival
Secondary study objectives
Post-treatment Pulmonary Function
Progressive free survival
Treatment Morbidity and Mortality

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Multifocal Lung AdenocarcinomaExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,324 Previous Clinical Trials
3,059,305 Total Patients Enrolled
Dennis Wigle, MD, PhDPrincipal InvestigatorMayo Clinic
9 Previous Clinical Trials
670 Total Patients Enrolled

Media Library

Multifocal Lung Adenocarcinoma (NA) Clinical Trial Eligibility Overview. Trial Name: NCT01946100 — N/A
~7 spots leftby Oct 2025
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