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Computerized Cognitive Training for Alcohol Use Disorder
N/A
Waitlist Available
Led By Ben Lewis, PhD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Must not have
Meet DSM-5 criteria for current/unremitted psychotic, panic, or bipolar disorders
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and up to 3 weeks
Awards & highlights
Summary
This trial is testing whether computerized cognitive training can help improve neurocognitive impairments caused by alcohol use disorder, and whether this leads to better treatment outcomes including reduced post-discharge alcohol consumption.
Who is the study for?
This trial is for individuals with at least 10 years of education who meet the criteria for alcohol use disorder according to DSM-5. It's not suitable for those with current or unremitted psychotic, panic, or bipolar disorders, or medical histories like stroke that could affect neuropsychological function.
What is being tested?
The study tests if computerized cognitive training can help people recovering from alcohol use disorder improve their brain functions. Participants will receive this training as an addition to inpatient treatment and its impact on recovery and post-treatment alcohol consumption will be assessed.
What are the potential side effects?
Since the interventions involve non-invasive computerized training programs focused on working memory, inhibitory control, and bias modification, there are no direct physical side effects expected from participating in this trial.
Eligibility Criteria
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I have been diagnosed with a psychotic, panic, or bipolar disorder that is ongoing.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and up to 3 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and up to 3 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
General Executive Function
Inhibitory Control
Working Memory
Trial Design
4Treatment groups
Experimental Treatment
Active Control
Group I: Working Memory Training (WM)Experimental Treatment1 Intervention
Participants complete training in a working memory task designed to utilize individually-adapted difficulty levels.
Group II: Inhibitory Control Training (IC)Experimental Treatment1 Intervention
Participants complete training in an inhibitory control task designed to utilize individually-adapted difficulty levels.
Group III: Bias Modification Training (BM)Active Control1 Intervention
Participants complete training in an active comparator task designed to weaken approach responses to alcohol-associated cues.
Group IV: Non-Trained control (NTC)Active Control1 Intervention
No active intervention is delivered beyond typical care.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Working Memory Training
2013
Completed Phase 2
~950
Inhibitory Control Training
2019
N/A
~590
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Who is running the clinical trial?
University of FloridaLead Sponsor
1,380 Previous Clinical Trials
762,254 Total Patients Enrolled
7 Trials studying Alcoholism
290 Patients Enrolled for Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
823 Previous Clinical Trials
1,161,165 Total Patients Enrolled
432 Trials studying Alcoholism
778,326 Patients Enrolled for Alcoholism
Ben Lewis, PhDPrincipal InvestigatorUniversity of Florida
1 Previous Clinical Trials
82 Total Patients Enrolled
1 Trials studying Alcoholism
82 Patients Enrolled for Alcoholism
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