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Noninvasive Brain Stimulation for Alzheimer's Disease
Verified Trial
N/A
Recruiting
Research Sponsored by Boston University Charles River Campus
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Do you have a diagnosis of Mild Cognitive Impairment or Alzheimer's disease?
Be older than 18 years old
Must not have
Do you have any skin sensitivity on your face or scalp (the study involves placing a fabric cap, several electrodes and some water-soluble gel at these sites)?
Have you ever had a diagnosis of epilepsy, or do you have current or past history of seizures?
Timeline
Screening 3 weeks
Treatment Varies
Follow Up time frame: memory performance data is collected during active brain stimulation and reported 1 year later
Summary
This trial tests if memory problems in Alzheimer's are caused by imbalances in brain activity. Results will help develop drug-free ways to help memory in AD and dementia.
Who is the study for?
This trial is for people aged 50-100 with Alzheimer's or mild cognitive impairment due to Alzheimer's, having certain memory performance scores. Healthy individuals can join if they meet specific cognitive norms. Participants must not have severe mental health issues, significant past brain conditions, or be on excluded medications.
What is being tested?
The study tests whether noninvasive brain stimulation using high definition transcranial electrical current can improve memory in those with Alzheimer's by affecting rhythmic activity in the brain. It aims to pave the way for drug-free treatments.
What are the potential side effects?
While not explicitly stated here, such noninvasive brain stimulation may cause discomfort at the electrode sites, headache, fatigue, nausea or dizziness during or after treatment.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowExclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ time frame: memory performance data is collected during sham brain stimulation and reported 1 year later
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~time frame: memory performance data is collected during sham brain stimulation and reported 1 year later
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Memory performance
Memory performance (active stimulation condition)
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: active stimulationExperimental Treatment1 Intervention
Memory performance data is collected during active brain stimulation and reported 1 year later
Group II: sham stimulationPlacebo Group1 Intervention
Memory performance data is collected during sham brain stimulation and reported 1 year later
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Who is running the clinical trial?
Boston University Charles River CampusLead Sponsor
119 Previous Clinical Trials
13,101 Total Patients Enrolled
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