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Comprehension Acquired Brain Injury for Traumatic Brain Injury

N/A
Waitlist Available
Led By Sarah Wallace, PhD
Research Sponsored by Miami University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured 1 week and 4 weeks post termination of treatment
Awards & highlights

Summary

The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only, (b) auditory output only (i.e., synthetic speech - David voice) or combined written text and auditory output. The phase 2 portion of the study is to evaluate comprehension of sentences and paragraphs produced with computer generated (synthesized) speech and digitized natural speech after multiple exposures.

Eligible Conditions
  • Traumatic Brain Injury
  • Aphasia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured 1 week and 4 weeks post termination of treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured 1 week and 4 weeks post termination of treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Comprehension Across Conditions (Study 1 of 2)
Repeated Exposure to Digitized and Synthetic Speech (Study 2 of 2)
Secondary study objectives
Comprehension Generalization
Perceived Comprehension Accuracy

Trial Design

1Treatment groups
Experimental Treatment
Group I: Comprehension Acquired Brain InjuryExperimental Treatment1 Intervention
All participants will be exposed to 3 conditions: (a) written text, (b) auditory output (synthetic speech), and combined conditions for study 1. For study 2 participants will be repeatedly exposed to synthetic speech output to determine the influence on comprehension. Participants are not required to participate in both studies.

Find a Location

Who is running the clinical trial?

Duquesne UniversityOTHER
31 Previous Clinical Trials
2,424 Total Patients Enrolled
University of ArizonaOTHER
525 Previous Clinical Trials
155,188 Total Patients Enrolled
Miami UniversityLead Sponsor
13 Previous Clinical Trials
2,606 Total Patients Enrolled
~8 spots leftby Sep 2025
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