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Procedure

Wisdom Teeth Transplant for Tooth Loss

N/A
Recruiting
Research Sponsored by Cleveland Dental Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged between 20 and 50 years
Possessing mandibular or maxillary immature wisdom teeth
Must not have
Patients afflicted with periodontal diseases
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one year
Awards & highlights
No Placebo-Only Group

Summary

"This trial explores the option of autotransplantation as an alternative to tooth extraction and prosthetic restoration when traditional treatments are not possible. Factors such as the stage of root development, tooth shape,

Who is the study for?
This trial is for healthy adults aged 20-50 with immature wisdom teeth needing removal, who can follow study procedures and have no major health issues. It's not for those with systemic diseases affecting healing, pacemaker users, periodontal disease sufferers, medication allergy patients or active smokers.
What is being tested?
The trial is testing the effectiveness of autotransplantation of wisdom teeth with and without Platelet Rich Fibrin (PRF), a substance that may aid healing. Participants will be randomly assigned to receive either just the tooth transplant or the transplant plus PRF.
What are the potential side effects?
Potential side effects could include pain at the extraction/transplant site, swelling, infection risk increase due to surgery, possible rejection of transplanted tooth or failure to integrate properly into its new location.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 20 and 50 years old.
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I have wisdom teeth that have not fully grown in.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have gum disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one year
This trial's timeline: 3 weeks for screening, Varies for treatment, and one year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Radiographic success

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Autotransplantation with PRFExperimental Treatment1 Intervention
Group II: Autotrasplantation onlyActive Control1 Intervention

Find a Location

Who is running the clinical trial?

Cleveland Dental InstituteLead Sponsor
5 Previous Clinical Trials
422 Total Patients Enrolled
Waleed Elmallah, DDSStudy ChairCleveland Dental
Ahmed Hashem, DDSStudy DirectorCleveland Dental
~11 spots leftby Nov 2025
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