Split-dose PEG Based Lavage (2L + 2L) + Low-fiber Diet for Colorectal Cancer (BP Trial)

N/A

Waitlist Available

Led By Alaa Rostom, MD

Research Sponsored by University of Calgary

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

* Patients between 18 to 74 Years referred to the Forzani \& MacPhail Colon Cancer Screening Centre in Calgary, Alberta, Canada for Colonoscopy will be considered for inclusion.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up questionnaire given on the day of pre-screen will be collected on the day of colonoscopy, approximately 3 weeks. patients are not followed or contacted past the day of colonoscopy.

Summary

The objective of the study is to examine the effect of adding a strict low-residue lunch on the day before colonoscopy has on clinical efficacy and patient tolerability of bowel preparation, with patients receiving split-dose Polyethylene Glycol Based Lavage. The primary outcomes will be 1) quality of preparation in cleansing the colon and 2) patient satisfaction

Eligible Conditions

Colorectal Cancer

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ questionnaire given on the day of pre-screen will be collected on the day of colonoscopy, approximately 3 weeks. patients are not followed or contacted past the day of colonoscopy.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~questionnaire given on the day of pre-screen will be collected on the day of colonoscopy, approximately 3 weeks. patients are not followed or contacted past the day of colonoscopy.

This trial's timeline: 3 weeks for screening, Varies for treatment, and questionnaire given on the day of pre-screen will be collected on the day of colonoscopy, approximately 3 weeks. patients are not followed or contacted past the day of colonoscopy. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Quality of Bowel Cleanliness

Secondary study objectives

Patient satisfaction with preparation

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Split-dose PEG Based Lavage (2L + 2L) + Low-fiber DietActive Control1 Intervention

Patients randomized to this arm will have a split-dose Polyethylene Glycol Based lavage (2L + 2L), have a low-fibre diet 4 days prior to Colonoscopy and the day before Colonoscopy, have a low-fibre breakfast, a low-fibre lunch by 2PM and then drink only clear fluids until after the procedure is completed.

Group II: Split-dose PEG Based Lavage (2L + 2L) + Clear fluid dietPlacebo Group1 Intervention

Patients randomized to this arm will have a split-dose Polyethylene Glycol Based lavage (2L + 2L), have a low-fibre diet 4 days prior to Colonoscopy and the day before Colonoscopy, have a low-fibre breakfast and then drink only clear fluids until after the procedure is completed.

0 / 1Eligibility criteria met