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Behavioural Intervention

Cognitive Control Training for Obsessive-Compulsive Disorder

N/A
Recruiting
Research Sponsored by Columbia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ages between 8 and 12 years
Be younger than 18 years old
Must not have
Females who are pregnant or nursing
Active suicidal ideation
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 2-week follow-up (mid-training), and 4-week follow-up (post-training)
Awards & highlights

Summary

This trial tests a video game-like program that helps kids with OCD by improving their focus, impulse control, and memory. They'll take scans and follow-up with Cognitive Behavioral Therapy.

Who is the study for?
This trial is for children aged 8-12 with clinically significant OCD as their main issue, not on medication or psychotherapy for OCD. They must meet specific criteria and have a score of ≥16 on the C-YBOCS scale. Kids can't join if they're pregnant, nursing, use illicit drugs, have metal implants/braces, major depression or other serious mental disorders, suicidal thoughts, major medical issues or an IQ <80.
What is being tested?
The study tests a game-like cognitive control training program (CT) using iPad games to improve attention and memory in young children with OCD. Over four weeks at home followed by MRI scans and standard Cognitive Behavioral Therapy (CBT), it aims to see if CT helps reduce symptoms and enhance response to CBT.
What are the potential side effects?
Since this intervention involves cognitive exercises through games without medication involved, no direct physical side effects are expected from the CT itself. However, stress or frustration may occur due to challenging tasks within the games.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 8 and 12 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am not pregnant or nursing.
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I am currently having thoughts about harming myself.
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I do not have any major medical issues like uncontrolled high blood pressure or seizures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 2-week follow-up (mid-training), and 4-week follow-up (post-training)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 2-week follow-up (mid-training), and 4-week follow-up (post-training) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
NIH Toolbox Cognition Battery

Trial Design

1Treatment groups
Experimental Treatment
Group I: Cognitive Training for Obsessive-Compulsive DisorderExperimental Treatment1 Intervention
This is an open-label, one-arm study. Children who meet DSM-V diagnostic criteria for OCD and have clinically significant obsessive-compulsive symptoms (CY-BOCS score\>16) will complete 4-weeks of at-home cognitive training.

Find a Location

Who is running the clinical trial?

Columbia UniversityLead Sponsor
1,471 Previous Clinical Trials
2,536,290 Total Patients Enrolled
5 Trials studying Obsessive-Compulsive Disorder
497 Patients Enrolled for Obsessive-Compulsive Disorder
New York State Psychiatric InstituteOTHER
477 Previous Clinical Trials
153,968 Total Patients Enrolled
24 Trials studying Obsessive-Compulsive Disorder
808 Patients Enrolled for Obsessive-Compulsive Disorder
National Institute of Mental Health (NIMH)NIH
2,869 Previous Clinical Trials
2,777,476 Total Patients Enrolled
65 Trials studying Obsessive-Compulsive Disorder
13,862 Patients Enrolled for Obsessive-Compulsive Disorder
~40 spots leftby Nov 2025
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