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TRE + Exercise for Weight Management
N/A
Waitlist Available
Research Sponsored by University of Illinois at Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Adults with obesity (BMI between 30-50kg/m2)
Sedentary or lightly active (<7,500 steps/day)
Must not have
Individuals taking drugs to control body weight and glucose (including metformin)
Mobility disorders or individuals unable to exercise for 40-60 minutes 3-4 days/week
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from week 1 to week 12
Awards & highlights
Summary
This trial will examine the effect of time restricted eating (TRE) combined with either resistance training or aerobic training on body weight, body composition, metabolic disease risk, and cognition in adults over age 50.
Who is the study for?
This trial is for adults aged 50-85 with prediabetes and obesity (BMI of 30-50), who are sedentary or lightly active. It's not for shift workers, those with eating disorders, major cognitive impairments, smokers, people unable to report diet or activity accurately, those not weight stable recently, diagnosed with diabetes (T1DM/T2DM), mobility issues, or on weight/glucose control drugs.
What is being tested?
The study tests time restricted eating (TRE) combined with either resistance training or aerobic exercise in older adults. TRE involves an eating window of 8-10 hours without calorie counting. The goal is to see if this leads to weight loss, better body composition, improved insulin sensitivity and cognition.
What are the potential side effects?
Potential side effects may include hunger during fasting periods and fatigue due to changes in diet and new exercise routines. Muscle soreness from resistance training and the usual risks associated with aerobic exercises could also occur.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My BMI is between 30 and 50.
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I am mostly inactive or lightly active, walking less than 7,500 steps a day.
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My blood sugar levels indicate I have pre-diabetes.
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I am between 50 and 85 years old.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am taking medication to manage my weight or blood sugar.
Select...
I cannot exercise for 40-60 minutes 3-4 days a week due to mobility issues.
Select...
I have a condition affecting my thinking, such as a brain injury or major psychiatric disorder.
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I have been diagnosed with diabetes based on my blood sugar or HbA1c levels.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ change from week 1 to week 12
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from week 1 to week 12
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Lean mass
Secondary study objectives
Attention
HbA1c
Insulin
+6 moreTrial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: TRE+RTExperimental Treatment1 Intervention
Participants will confine eating between either 10am-6pm or 12-8pm and fast from 6pm-10am or 8pm-12pm daily combined with 3-4 days of supervised resistance training per week.
Group II: TRE+ATActive Control1 Intervention
Participants will confine eating between either 10am-6pm or 12-8pm and fast from 6pm-10am or 8pm-12pm daily combined with 3-4 days of supervised aerobic training per week.
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Who is running the clinical trial?
University of Illinois at ChicagoLead Sponsor
632 Previous Clinical Trials
1,567,675 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I am taking medication to manage my weight or blood sugar.My BMI is between 30 and 50.I am mostly inactive or lightly active, walking less than 7,500 steps a day.My blood sugar levels indicate I have pre-diabetes.You can't accurately tell the study team about what you eat or how active you are.I cannot exercise for 40-60 minutes 3-4 days a week due to mobility issues.You have a history of eating disorders.I have a condition affecting my thinking, such as a brain injury or major psychiatric disorder.I am between 50 and 85 years old.I have been diagnosed with diabetes based on my blood sugar or HbA1c levels.People who smoke.You have gained or lost more than 4 kilograms (about 9 pounds) in the past 3 months.People who work night shifts or irregular hours.
Research Study Groups:
This trial has the following groups:- Group 1: TRE+RT
- Group 2: TRE+AT
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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