← Back to Search

Behavioral Intervention

Psychosocial Care for Advanced Cancer

N/A

Waitlist Available

Led By Anne Reb, NP, PhD

Research Sponsored by City of Hope Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Stage III or IV disease

Must not have

Patients enrolled in hospice care or who opt to receive no further disease-focused treatment

Current severe depression or psychosis; significant cognitive impairment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 9 months

Awards & highlights

No Placebo-Only Group

Summary

This trial will test a new psychosocial intervention called Conquer Fear Support (CFS) in patients with stage III-IV lung or gynecologic cancer who are afraid of their cancer progressing. CFS is based on a program called "Conquer Fear" which was developed by researchers in Australia. It may help reduce worries, fears, and uncertainty in patients with advanced lung or gynecological cancer.

Who is the study for?

This trial is for English-speaking patients with stage III-IV lung or gynecologic cancer who have been diagnosed at least 3 months ago. They must be undergoing treatment or active surveillance and feel a strong fear of their cancer progressing, as measured by specific questionnaires.

What is being tested?

The Conquer Fear Support intervention is being tested to see if it can help reduce the fear and anxiety associated with advanced-stage lung or gynecological cancers. It includes psychoeducation, attention training, worry management, and detached mindfulness components.

What are the potential side effects?

Since this is a psychosocial intervention focusing on mental health support rather than medication, there are no typical drug side effects. However, participants may experience emotional discomfort while discussing fears and anxieties.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My condition is in stage III or IV.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am in hospice care or have chosen not to pursue further treatment for my condition.

Select...

I do not have severe depression, psychosis, or significant cognitive issues.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 9 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 9 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 9 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Feasibility of the Conquer Fear SUPPORT (CFS) intervention is assessed by tracking attendance.

Feasibility of the Conquer Fear SUPPORT (CFS) intervention is assessed by tracking attrition.

Feasibility of the Conquer Fear SUPPORT (CFS) intervention is assessed by tracking enrollment rate.

Secondary study objectives

Anxiety assessed using the PROMIS-Anxiety 8a

Cancer-specific distress assessed using the Impact of Event Scale-Revised (IES-R)

Depression assessed using the Patient Health Questionnaire (PHQ-9)

+4 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Supportive care (CFS)Experimental Treatment2 Interventions

Patients attend CFS psychosocial intervention consisting of 7 nurse-led sessions (session 1 in-person and sessions 2-7 via video conferencing) over 45 minutes each for 8 weeks. Patients also complete home practice assignments comprising attention training technique and mindfulness practice after each session. Patients complete self-report questionnaires at baseline (T1), 8 weeks (T2) and 12 weeks (T3).

0 / 3Eligibility criteria met