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Water Dosing for Orthostatic Hypotension

N/A
Waitlist Available
Led By Satish R Raj, MD MSCI
Research Sponsored by Satish R. Raj
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18-80 years
Orthostatic hypotension (fall in BP>20/10 mmHg)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether drinking water will help blood pressure in patients with low blood pressure when standing up, when they have had a lot to drink beforehand.

Who is the study for?
This trial is for adults aged 18-80 with orthostatic hypotension, which means their blood pressure drops significantly when standing up. They should have previously shown a blood pressure increase after drinking water in other studies. Pregnant individuals cannot participate.
What is being tested?
The study investigates the effect of two different doses of water on blood pressure in patients with orthostatic hypotension. It aims to determine if the pressor (blood-pressure raising) response to water diminishes when a full dose is taken earlier.
What are the potential side effects?
Drinking high or low doses of water typically does not cause side effects; however, it may lead to discomfort from bloating or stomach fullness and very rarely might contribute to changes in electrolyte balance.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 80 years old.
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My blood pressure drops significantly when I stand up.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 1Experimental Treatment1 Intervention
16 oz water in AM
Group II: 2Active Control1 Intervention
water 1 oz in AM

Find a Location

Who is running the clinical trial?

Satish R. RajLead Sponsor
6 Previous Clinical Trials
670 Total Patients Enrolled
Satish R Raj, MD MSCIPrincipal InvestigatorVanderbilt University Medical Center
19 Previous Clinical Trials
1,406 Total Patients Enrolled

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