← Back to Search

Genetic Testing

Genetic Testing for Infertility (GETSET Trial)

N/A
Recruiting
Led By Nathan Treff, PhD
Research Sponsored by Genomic Prediction Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Utilization of autologous or donor sperm
All Controlled Ovarian Hyperstimulation (COH) protocols
Must not have
Preimplantation genetic testing for monogenic/single gene disorders (PGT-M)
Recurrent Implantation Failure (RIF) defined as ≥ 3 more failed embryo transfers
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 years
Awards & highlights
No Placebo-Only Group

Summary

This trial will evaluate the benefits of a genetic test before embryo transfer to improve pregnancy outcomes in women aged 35-40.

Who is the study for?
The GETSET trial is for women aged 35-40 undergoing IVF with their own or donor sperm, and any COH protocol. It's not for those using donor eggs, gestational carriers, have had ≥3 miscarriages in a row, ≥3 failed embryo transfers, need genetic testing for single gene disorders or are translocation carriers.
What is being tested?
This study tests if preimplantation genetic testing for aneuploidies (PGT-A) improves pregnancy outcomes when used during elective single embryo transfer in IVF treatments for women between the ages of 35 and 40.
What are the potential side effects?
Since PGT-A involves testing embryos before implantation without using drugs or medical procedures on participants directly, it generally does not have side effects like medications do. However, usual IVF-related risks still apply.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am using my own or donor sperm for treatment.
Select...
I am undergoing or have undergone ovarian stimulation treatment.
Select...
I am using or plan to use ICSI or traditional IVF for conception.
Select...
I am using ejaculated or testicular sperm for conception.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have undergone genetic testing for specific inherited disorders.
Select...
I have had 3 or more unsuccessful embryo transfers.
Select...
I have a genetic change known as a translocation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Ongoing Pregnancy Rate
Secondary study objectives
Miscarriage Rate

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Experimental Arm - Transfer of Best Quality, Euploid BlastocystExperimental Treatment1 Intervention
Transfer of best quality, PGTA normal (euploid) blastocyst.
Group II: Control Arm - Transfer of Untested, Best Quality BlastocystActive Control1 Intervention
Transfer of Untested, Best Quality Blastocyst

Find a Location

Who is running the clinical trial?

Genomic Prediction Inc.Lead Sponsor
5 Previous Clinical Trials
11,440 Total Patients Enrolled
Boston IVFOTHER
19 Previous Clinical Trials
19,984 Total Patients Enrolled
Nathan Treff, PhDPrincipal InvestigatorGenomic Prediction Clinical Labortory
~0 spots leftby Nov 2024
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top