Your session is about to expire
← Back to Search
Dietary Interventions for Cancer
N/A
Waitlist Available
Led By Hassane M Zarour, MD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Eastern Cooperative Oncology Group (ECOG) performance status of 0 - 1
Early stage (I-III) resected melanoma patient on adjuvant immunotherapy
Must not have
Patients receiving ICIs enrolled in a clinical trial
Unable or unwilling to adhere schedule interventions and study procedures
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 14 weeks
Awards & highlights
Summary
This trial will investigate how different diets, focusing on high-fermented foods and high-fiber supplements, can impact the gut bacteria and immune response in patients with melanoma and lung cancer who are receiving
Who is the study for?
This trial is for melanoma and NSCLC cancer patients undergoing standard immune checkpoint inhibitor therapy. It's designed to see if certain diets can help their treatment work better.
What is being tested?
The study tests the effects of high-fermented foods and high-fiber supplements on gut bacteria and how they might boost the body's response to cancer immunotherapy in these patients.
What are the potential side effects?
Potential side effects may include digestive discomfort, such as bloating or gas, due to changes in diet with high-fermented foods and fiber supplements.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am fully active or can carry out light work.
Select...
I have early-stage melanoma and am receiving immunotherapy after surgery.
Select...
I have early stage lung cancer and am on adjuvant immunotherapy after surgery.
Select...
I have early stage lung cancer and am getting chemo and immunotherapy before surgery.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am currently in a clinical trial for immune checkpoint inhibitors.
Select...
I am unable or unwilling to follow the study's schedule and procedures.
Select...
I have not had major GI surgery in the last 5 years, except for gallbladder or appendix removal.
Select...
I have not consumed more than five alcoholic drinks daily in the last 4 weeks.
Select...
I do not have active, uncontrolled gut disorders like severe IBS or Crohn's disease.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 14 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 14 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in cell frequency of gut microbiota composition
Secondary study objectives
Adverse Events and Serious Adverse Events
Changes in cell frequency of circulating adaptive immune cells
Trial Design
1Treatment groups
Experimental Treatment
Group I: high-fermented food + high fiber supplementationExperimental Treatment2 Interventions
Step 1: patients will consume high-fermented food
Step 2: High fiber supplementation
Find a Location
Who is running the clinical trial?
University of PittsburghLead Sponsor
1,762 Previous Clinical Trials
16,347,943 Total Patients Enrolled
Hassane M Zarour, MDPrincipal InvestigatorUPMC Hillman Cancer Center
2 Previous Clinical Trials
29 Total Patients Enrolled
Share this study with friends
Copy Link
Messenger