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ProDentis Lozenge for Oral Neoplasms

N/A
Waitlist Available
Led By David Drake, MS, PhD
Research Sponsored by University of Iowa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 months

Summary

This trial investigates whether taking probiotics can change the types of bacteria in the mouths of people with pre-cancerous or cancerous oral lesions. The goal is to see if these changes can lower their risk of developing oral cancer. Researchers will compare mouth swabs before and after a few months of probiotic use. Probiotics have shown potential in inhibiting oral carcinogenesis, with specific strains like L. salivarius REN significantly reducing the risk of developing oral cancer.

Eligible Conditions
  • Oral Cancers

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Assessment of changes in the oral microbiome composition over time
Determine the Effect of ProDentis on the Oral Microbiome

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Probiotic LozengeExperimental Treatment1 Intervention
Group II: Placebo LozengePlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ProDentis Lozenge
2022
N/A
~20

Find a Location

Who is running the clinical trial?

University of IowaLead Sponsor
465 Previous Clinical Trials
893,251 Total Patients Enrolled
David Drake, MS, PhDPrincipal InvestigatorUniversity of Iowa College of Dentistry

Media Library

ProDentis Lozenge Clinical Trial Eligibility Overview. Trial Name: NCT04925700 — N/A
Oral Cancers Research Study Groups: Placebo Lozenge, Probiotic Lozenge
Oral Cancers Clinical Trial 2023: ProDentis Lozenge Highlights & Side Effects. Trial Name: NCT04925700 — N/A
ProDentis Lozenge 2023 Treatment Timeline for Medical Study. Trial Name: NCT04925700 — N/A
~6 spots leftby Nov 2025
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