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Cool Room Treadmill Training for Multiple Sclerosis

N/A

Waitlist Available

Led By Michelle Ploughman, PhD

Research Sponsored by Memorial University of Newfoundland

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged older than 18 and less than 70 years

People with a confirmed diagnosis of relapsing-remitting or progressive MS

Must not have

A relapse of MS

Functional community ambulators (gait speed>120 cm/s)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up following completion of the 12-week exercise intervention and 3-months post-exercise intervention

Awards & highlights

No Placebo-Only Group

Summary

This trial will test how effective a more intense form of exercise is in people with MS who have fatigue and heat-sensitivity.

Who is the study for?

This trial is for people aged 18-70 with a confirmed diagnosis of relapsing-remitting or progressive Multiple Sclerosis. Participants should be stable without MS relapse for at least 90 days and able to walk at least 10 meters, even if they need walking aids.

What is being tested?

The study tests vigorous intensity treadmill training in a cool room (16°C) against low-intensity training to see which is better for restoring functions lost due to MS. The focus is on finding the right amount of exercise that can be tolerated by those who experience fatigue and heat sensitivity from MS.

What are the potential side effects?

Potential side effects may include muscle soreness, fatigue, and temporary worsening of MS symptoms due to physical exertion or reactions to cooler temperatures during the exercise.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 19 and 69 years old.

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I have been diagnosed with relapsing-remitting or progressive MS.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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My MS has relapsed.

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I can walk quickly without assistance.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ following completion of the 12-week exercise intervention and 3-months post-exercise intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~following completion of the 12-week exercise intervention and 3-months post-exercise intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and following completion of the 12-week exercise intervention and 3-months post-exercise intervention for reporting.