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Non-invasive Brain Mapping for Parkinson's Disease

N/A
Recruiting
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age > 18 years old
Healthy adult with no neurologic disease
Must not have
Active hallucinations or psychosis
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 4 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether different types of movement cues can help people with Parkinson's disease move more normally, and whether brain mapping techniques can help understand how this works.

Who is the study for?
This trial is for adults over 18 with Parkinson's disease, showing at least two main symptoms: tremor, stiffness or slow movement. Healthy adults without neurological diseases can also join. People with dementia, active hallucinations, psychosis or who cannot undergo MRI due to metal implants or claustrophobia are excluded.
What is being tested?
The study investigates how certain stimuli facilitate movement in Parkinson's patients by using brain mapping techniques like EEG and MRI during movement tasks. The goal is to understand the brain networks that improve motion which could lead to new treatments.
What are the potential side effects?
Since this trial involves non-invasive brain mapping rather than medication or invasive procedures, side effects are minimal but may include discomfort from wearing EEG equipment or staying still in an MRI machine.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am older than 18 years.
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I am a healthy adult without any brain or nerve diseases.
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I have Parkinson's with at least 2 main symptoms or I am healthy with no brain disorders.
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I have Parkinson's disease with symptoms like shaking, stiffness, or slow movement.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am currently experiencing hallucinations or psychosis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
BOLD fMRI: functional brain connectivity
Diffusion tractography imaging (MRI): structural brain connectivity
EEG recordings

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Parkinson disease patientsExperimental Treatment1 Intervention
Participants diagnosed with Parkinson's disease
Group II: Healthy adultsActive Control1 Intervention
Healthy adult age-matched controls

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,562 Previous Clinical Trials
10,262,271 Total Patients Enrolled
National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,376 Previous Clinical Trials
651,395 Total Patients Enrolled

Media Library

Movement task Clinical Trial Eligibility Overview. Trial Name: NCT05179187 — N/A
Parkinson's Disease Research Study Groups: Parkinson disease patients, Healthy adults
Parkinson's Disease Clinical Trial 2023: Movement task Highlights & Side Effects. Trial Name: NCT05179187 — N/A
Movement task 2023 Treatment Timeline for Medical Study. Trial Name: NCT05179187 — N/A
Parkinson's Disease Patient Testimony for trial: Trial Name: NCT05179187 — N/A
~39 spots leftby Sep 2026
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