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Procedure

Flexible stimulation for Parkinson's Disease

N/A
Waitlist Available
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after 3 months of each intervention
Awards & highlights
No Placebo-Only Group

Summary

Exploring the benefits of the linear lead in deep brain stimulation.

Eligible Conditions
  • Parkinson's Disease
  • Overactive Bladder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after 3 months of each intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and after 3 months of each intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change of Overall Global functioning (PGIC)
Secondary study objectives
Cadence measured using Prokinetics gait analysis/Zeno Walkway
Change in the presence and severity of depressive symptoms using the Beck Depression Inventory (BDI)
Clinical change in motor symptoms
+6 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Flexible stimulationExperimental Treatment1 Intervention
Flexible stimulation using all available stimulation strategies provided by the VerciseTM system including stimulation of contacts 1-8 and variable pulse width and frequency.
Group II: Standard StimulationActive Control1 Intervention
Standard stimulation using contact 3-6 to achieve best therapeutic stimulation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Deep brain stimulation
2010
Completed Phase 3
~390

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
714 Previous Clinical Trials
1,022,812 Total Patients Enrolled
~1 spots leftby Nov 2025