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Exercise Training for Mental Illness

N/A
Recruiting
Led By Ryan Garten, PhD
Research Sponsored by Virginia Commonwealth University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
Be between 18 and 65 years old
Must not have
Taking medications that could influence cardiovascular function
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to the end of the final visit, about 14 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial will test the effects of different types of exercise on blood vessel function in people with and without mental health disorders.

Who is the study for?
This trial is for healthy individuals and those with PTSD or GAD who want to explore how different exercise routines affect blood vessel function. Participants should not have cardiovascular, pulmonary, or metabolic diseases. They must not be pregnant, on certain medications, recent smokers, drug users, heavy drinkers, or have significant dietary restrictions.
What is being tested?
The study tests three types of exercise training: high intensity normal volume; moderate intensity normal volume; and moderate intensity high volume. It aims to see which routine best improves vascular function in both healthy people and those with mental health disorders.
What are the potential side effects?
Exercise may cause muscle soreness, fatigue, shortness of breath during activity, increased heart rate and the risk of musculoskeletal injuries. The impact can vary based on individual fitness levels and the type of exercise performed.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am healthy with no obvious heart, lung, or metabolic diseases.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am on medication that affects my heart's function.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to the end of the final visit, about 14 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to the end of the final visit, about 14 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Arm Vascular Function at Rest (Flow Mediated Dilation Test)
Arm Vascular Function in Response to Exercise (Handgrip Exercise Test)
Leg Vascular Function (Passive Leg Movement Test)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Moderate Intensity, Normal Volume Exercise TrainingExperimental Treatment1 Intervention
Participants will complete study 1 (HM20020955-1) and then 10 weeks of moderate intensity, normal volume exercise training
Group II: Moderate Intensity, High Volume Exercise TrainingExperimental Treatment1 Intervention
Participants will complete study 1 (HM20020955-1) and then 10 weeks of moderate intensity, high volume exercise training
Group III: High Intensity, Normal Volume Exercise TrainingExperimental Treatment1 Intervention
Participants will complete study 1 (HM20020955-1) and then 10 weeks of high intensity, normal volume exercise training

Find a Location

Who is running the clinical trial?

Virginia Commonwealth UniversityLead Sponsor
714 Previous Clinical Trials
22,888,035 Total Patients Enrolled
Ryan Garten, PhDPrincipal InvestigatorVirginia Commonwealth University
5 Previous Clinical Trials
1,067 Total Patients Enrolled

Media Library

High Intensity, Normal Volume Exercise Training Clinical Trial Eligibility Overview. Trial Name: NCT04922762 — N/A
Peripheral Vascular Disease Research Study Groups: Moderate Intensity, Normal Volume Exercise Training, High Intensity, Normal Volume Exercise Training, Moderate Intensity, High Volume Exercise Training
Peripheral Vascular Disease Clinical Trial 2023: High Intensity, Normal Volume Exercise Training Highlights & Side Effects. Trial Name: NCT04922762 — N/A
High Intensity, Normal Volume Exercise Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT04922762 — N/A
~67 spots leftby Aug 2025
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