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Air/Oxygen Mixture for Pulmonary Atelectasis

N/A
Waitlist Available
Led By Neal Badner, MD, FRCP(C)
Research Sponsored by London Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately after the surgery - up to 2 days post operative.
Awards & highlights
No Placebo-Only Group

Summary

Patients scheduled for lung lobe resection using video assisted thoracic surgery will be randomly assigned to be ventilated with either only oxygen or a mixture of air and oxygen. The primary purpose of this study is to determine if the incidence of postoperative collapse (in the non-surgical lung) is decreased when using a mixture of air and oxygen compared to using only oxygen (which is our control measurement) during one-lung ventilation.

Eligible Conditions
  • Pulmonary Atelectasis
  • Postoperative Atlectasis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately after the surgery - up to 2 days post operative.
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after the surgery - up to 2 days post operative. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
The incidence of postoperative atelectasis

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Air/Oxygen MixtureExperimental Treatment1 Intervention
Patients in this group will be ventilated with a mixture of air and oxygen during one lung ventilation.
Group II: OxygenActive Control1 Intervention
Patients in this group will be ventilated with only oxygen during one lung ventilation.

Find a Location

Who is running the clinical trial?

London Health Sciences CentreLead Sponsor
146 Previous Clinical Trials
52,284 Total Patients Enrolled
Neal Badner, MD, FRCP(C)Principal InvestigatorLondon Health Science Centre, University Of Western Ontario
~5 spots leftby Nov 2025