← Back to Search

Other

Eggshell Membrane Supplement for Skin Health

N/A
Waitlist Available
Led By Kevin J Ruff, PhD
Research Sponsored by ESM Technologies, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subject must not have used for 30 days prior to screening and be willing to discontinue use of all topical and ingested products expected to improve the health of the skin, hair, or fingernails for the duration of the study (Examples of these types of medicines are: tretinoin (Retin A®), isotretinoin (Accutane®), hyaluronic acid, collagen, topical steroids, topical antibiotics, topical retinol, topical benzoyl peroxide, topical glycolic acid, topical salicylic acid, etc.)
Subject must be available for and willing to attend all evaluation visits
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks or 12 weeks
Awards & highlights

Summary

This trial is testing if taking a supplement made from eggshell membrane can improve the appearance of skin in middle-aged and senior adults. They will use a special device and questionnaires to measure the effects.

Who is the study for?
This trial is for men and women aged 40-70 with light complexions, generally healthy without chronic skin conditions. Participants must not have used any skin, hair, or nail improvement products for 30 days prior to the study and agree to avoid them during the trial. Non-smokers only; 'vape' pen users are allowed.
What is being tested?
The study tests if taking unhydrolyzed eggshell membrane (uESM) supplements can improve skin aging signs compared to a placebo. It uses objective measures like Cutometer® MPA 580 readings and subjective feedback through questionnaires on skin, hair, and nail health.
What are the potential side effects?
Potential side effects aren't specified in the provided information but could include allergic reactions or gastrointestinal discomfort due to uESM ingestion since it's an oral supplement derived from eggshells.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I haven't used skin, hair, or nail health products for 30 days and will stop using them during the study.
Select...
I am willing and able to attend all required study visits.
Select...
I am between 40 and 70 years old with a light skin tone.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks or 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks or 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
skin elasticity/firmness
Secondary study objectives
overall fingernail health
overall hair health
overall skin health
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: uESM (Ovolux brand)Experimental Treatment1 Intervention
This arm will receive a treatment protocol consisting of enough capsules to provide a daily dose of one 300 mg capsule of uESM.
Group II: PlaceboPlacebo Group1 Intervention
This arm will receive a treatment protocol consisting of enough capsules to provide a daily dose of one capsule containing psyllium husk fiber.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
unhydrolyzed eggshell membrane
2023
N/A
~70

Find a Location

Who is running the clinical trial?

ESM Technologies, LLCLead Sponsor
9 Previous Clinical Trials
449 Total Patients Enrolled
Kevin J Ruff, PhDPrincipal InvestigatorESM Technologies, LLC d/b/a Stratum Nutrition
~38 spots leftby Sep 2025