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Sleep Management for Sleep Deprivation

N/A
Recruiting
Led By Robert Stickgold, PhD
Research Sponsored by Beth Israel Deaconess Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12-24 hours
Awards & highlights
No Placebo-Only Group

Summary

This trial will study how sleep deprivation and undisturbed sleep affects the processing and retrieval of emotional information, what mechanisms are associated with these behavioral effects, and if recovery sleep can reverse the effects of sleep deprivation.

Who is the study for?
This trial is for individuals who can follow the study's rules and are willing to avoid alcohol and recreational drugs during the study. They must have normal vision (with or without correction) and be right-handed. People with sleep issues, mental illness, neurological disorders, or those taking medication affecting sleep or cognition cannot participate.
What is being tested?
The study examines how lack of sleep and recovery sleep affect emotional memory and mood reactions. It will look at how a good night's rest versus being awake all night influences emotions, what brain activities are linked to these effects, and if a nap can help reverse any negative impacts of missed sleep.
What are the potential side effects?
Since this trial involves sleep deprivation followed by recovery naps without medicinal interventions, side effects may include tiredness, irritability, difficulty concentrating, mood changes during the deprivation period but not long-term physical side effects.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12-24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12-24 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Emotional Memory Tradeoff Memory Score
Morphed Face Accuracy and Intensity
Psychomotor vigilance task lapse rate
Secondary study objectives
Heart Rate Reactivity (Beats per minute)
Skin
Oxygen saturation measurement

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Daytime NapExperimental Treatment2 Interventions
Subjects are trained and then retested after a daytime nap
Group II: Sleep deprivationActive Control1 Intervention
Subjects sleep deprived before participating in training and testing sessions the next day
Group III: Overnight sleepActive Control1 Intervention
Subjects are permitted a night of polysomnograph-recorded sleep before participating in training and testing sessions the next day
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Sleep Deprivation
2012
N/A
~210

Find a Location

Who is running the clinical trial?

Boston CollegeOTHER
39 Previous Clinical Trials
48,960 Total Patients Enrolled
Beth Israel Deaconess Medical CenterLead Sponsor
853 Previous Clinical Trials
12,930,821 Total Patients Enrolled
6 Trials studying Sleep Deprivation
4,394 Patients Enrolled for Sleep Deprivation
Robert Stickgold, PhDPrincipal InvestigatorBeth Israel Deaconess Medical Center
1 Previous Clinical Trials
276 Total Patients Enrolled
1 Trials studying Sleep Deprivation
276 Patients Enrolled for Sleep Deprivation

Media Library

Sleep Deprivation Clinical Trial Eligibility Overview. Trial Name: NCT03767426 — N/A
Sleep Deprivation Clinical Trial 2023: Sleep Deprivation Highlights & Side Effects. Trial Name: NCT03767426 — N/A
Sleep Deprivation 2023 Treatment Timeline for Medical Study. Trial Name: NCT03767426 — N/A
~16 spots leftby Dec 2025
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