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Virtual Reality Navigation for Partial Vision Loss

N/A
Recruiting
Research Sponsored by University of Rochester
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans)
Willing, able, and competent to provide their own informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 0
Awards & highlights

Summary

This trial will use a VR program to study how people with cortically-induced blindness drive in simulated environments. Computer vision, deep learning & gaze-contingent manipulations will be used to understand changes to their driving.

Who is the study for?
This trial is for US or Canadian residents aged 21-75 who've had a one-sided stroke affecting vision, confirmed by MRI/CT scans. Participants must have consistent visual field defects in both eyes and be able to understand instructions in English. They should consent themselves and can wear contacts if needed.
What is being tested?
Researchers are using Virtual Reality (VR) to study how people with cortically-induced blindness from strokes adapt when driving. The VR program simulates real-world environments, tracking steering behavior to learn about changes in visual processing.
What are the potential side effects?
Since this study involves a non-invasive VR task, traditional side effects associated with medical treatments are not expected. However, participants may experience discomfort related to VR use such as dizziness or nausea.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I had a stroke affecting my vision between ages 21-75, confirmed by MRI or CT.
Select...
I am capable and willing to give my consent for treatment.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 0
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 0 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Virtual Reality (VR) Lane Deviation / Offset

Trial Design

2Treatment groups
Experimental Treatment
Group I: Virtual Reality (VR) Driving Task: Healthy Control CohortExperimental Treatment1 Intervention
Healthy controls with no vision loss will perform a driving task in VR, in which they must steer through a series of parameterized turns while maintaining their virtual vehicle centered between the two red lines delineating the "road" edge.
Group II: Virtual Reality (VR) Driving Task: Cortically Blind CohortExperimental Treatment1 Intervention
Persons who have sustained cortical blindness will perform a driving task in VR, in which they must steer through a series of parameterized turns while maintaining their virtual vehicle centered between the two red lines delineating the "road" edge.

Find a Location

Who is running the clinical trial?

Rochester Institute of TechnologyOTHER
9 Previous Clinical Trials
4,779 Total Patients Enrolled
University of RochesterLead Sponsor
859 Previous Clinical Trials
538,663 Total Patients Enrolled
7 Trials studying Stroke
392 Patients Enrolled for Stroke
~27 spots leftby Oct 2026
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