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Patient- and Provider-Facing CDS for Vaccine Hesitancy

N/A
Waitlist Available
Led By Daniel Salmon, PhD
Research Sponsored by Johns Hopkins Bloomberg School of Public Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Patient has an upcoming appointment in 2 business days at Children's Healthcare of Atlanta Hughes Spalding Primary Care Clinic.
* A valid mobile phone number or e-mail address is available in the EHR as of 2 business days prior to the appointment date.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to one year
Awards & highlights

Summary

The goal of this project is to establish the technical feasibility of a scalable, integrated platform to improve patient informed decision-making and increase vaccine uptake and to evaluate the effectiveness of the integrated platform to improve vaccine uptake.

Who is the study for?
This trial is for individuals who are hesitant or refuse vaccines. It aims to improve vaccine acceptance by using a platform that reminds patients of appointments and provides decision support tools for both patients and providers.
What is being tested?
The study tests an integrated platform with two main features: 'LetsTalkShots', which offers decision support to patients and healthcare providers, and an appointment reminder system, all within the electronic health record (EHR) system.
What are the potential side effects?
Since this trial involves informational interventions rather than medical treatments, traditional physical side effects are not applicable. However, there may be psychological impacts related to changing attitudes towards vaccines.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to one year
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to one year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Vaccination rate
Secondary study objectives
Days undervaccinated
Patient Adoption as assessed by proportion of successful texts sent
Provider Adoption as assessed by proportion of orders opened

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Patient-Facing CDS OnlyExperimental Treatment2 Interventions
Among patients without a MYchart account, those with odd birthdates will receive a link to the LTS website (patient-facing CDS) but no integration into the provider workflow.
Group II: Patient- and Provider-Facing CDSExperimental Treatment3 Interventions
Parents of patients with odd birthdates (e.g. April 13) and vaccines due at the index appointment who also have a MYchart account will receive a text message directing the parent to the LTS server with integration into the provider workflow
Group III: Control (MYchart account)Placebo Group1 Intervention
Patients with an even birthdate (e.g. April 14) who have a MYchart account will receive a regular text message and e-mail appointment reminder with a vaccine primer (e.g. "Vaccines are due and reserved for the participant's child"), but no patient- or provider-facing CDS.
Group IV: Control (no MYchart account)Placebo Group1 Intervention
As in the other control group, those without a MYchart account and an even birthdate (e.g. April 14) will receive a text message and e-mail appointment reminder with a vaccine primer but no patient- or provider-facing CDS.

Find a Location

Who is running the clinical trial?

Emory UniversityOTHER
1,679 Previous Clinical Trials
2,578,831 Total Patients Enrolled
Children's Healthcare of AtlantaOTHER
167 Previous Clinical Trials
105,144 Total Patients Enrolled
Johns Hopkins Bloomberg School of Public HealthLead Sponsor
418 Previous Clinical Trials
2,123,828 Total Patients Enrolled
2 Trials studying Vaccine Hesitancy
2,658 Patients Enrolled for Vaccine Hesitancy
~800 spots leftby May 2026
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