Trials in Los Angeles, California
Here are the top 10 medical studies for breast cancer in Los Angeles, California
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Phase 3 Trials
PARP Inhibitor
Niraparib for Breast Cancer
Recruiting1 awardPhase 3
Burbank, California
This trial is testing Niraparib, a drug that stops cancer cells from fixing their broken DNA, in patients with certain types of breast cancer that are either genetically aggressive or have signs of remaining disease after treatment. Niraparib is a drug already used for ovarian cancer and has shown promise in treating breast cancer with certain genetic markers.
Antibody-Drug Conjugate
Dato-DXd for Breast Cancer
Recruiting2 awardsPhase 3
Los Angeles, California
This trial is testing a new drug called datopotamab deruxtecan to see if it helps patients with advanced breast cancer live longer or have a better quality of life compared to standard chemotherapy. Datopotamab deruxtecan has shown encouraging response rates and manageable toxicity in patients with advanced/metastatic triple-negative breast cancer.
Selective Estrogen Receptor Degrader (SERD)
Giredestrant + Hormone Therapy for Early-Stage Breast Cancer
Recruiting2 awardsPhase 3
Santa Monica, California
This trial is testing giredestrant, a medication given after initial treatment to prevent breast cancer from returning. It focuses on patients with a specific type of early-stage breast cancer that is hormone-driven and at higher risk of recurrence. Giredestrant works by blocking the hormone estrogen from helping cancer cells grow. Giredestrant has shown promise in previous studies.
CDK4/6 Inhibitor
Abemaciclib + Fulvestrant for Breast Cancer
Recruiting1 awardPhase 3
Los Angeles, California
This trial is testing a combination of two drugs, abemaciclib and fulvestrant, for treating a specific type of breast cancer that has not responded to previous treatments. Abemaciclib is taken orally and is approved for treating certain types of breast cancer. The goal is to see if this combination can help stop the cancer from growing. The study may last several years, depending on how well the treatment works for each patient.
Trials With No Placebo
Monoclonal Antibodies
XB002 for Advanced Cancers
Recruiting2 awardsPhase 1
Los Angeles, California
This trial is testing a new drug called XB002, given through an IV periodically, to see if it can help patients with advanced solid tumors. The drug is tested alone and with other cancer treatments. Researchers are checking if it is safe and effective in shrinking or stopping tumor growth.
Virus Therapy
Vidutolimod + Cemiplimab for Advanced Cancer
Recruiting1 awardPhase 2
Los Angeles, California
This trial is studying CMP-001 given by injection into the tumor in combination with an intravenous PD-1-blocking antibody to see how well it works in treating patients with certain types of advanced or metastatic cancer.
Monoclonal Antibodies
NGM707 + Pembrolizumab for Cancer
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing a new drug called NGM707, both by itself and with another drug, Pembrolizumab. It targets patients with very advanced or spreading solid tumors. The treatment aims to boost the immune system to better fight cancer.
White Button Mushroom Extract for Breast Cancer Risk Reduction
Recruiting1 award24 criteria
Duarte, California
This trial is testing if eating white button mushrooms every day can help improve health in obese postmenopausal women at high risk of breast cancer. The mushrooms might help by making immune cells work better and reducing long-term inflammation. Researchers hope this could lower the risk of breast cancer and improve overall health.
Behavioural Intervention
Educational Intervention for Cancer Knowledge
Recruiting1 award6 criteria
Duarte, California
This trial studies a web-based cancer education tool called HOPE-Genomics. The tool provides patients with information about genomic testing and their own genomic test results. The goal is to improve patient's genomic knowledge and quality of patient-centered care.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.