Popular Trials
Procedure
Laparoscopy for Postoperative Pain
Recruiting2 awards1 criteria
Stony Brook, New York
This study will help to answer the question, "Does injecting local anesthetic before laparoscopic instrument ports are placed decrease pain after surgery?" Patients participating will be randomly assigned to receive local anesthetic or saline injection at the site of a laparoscopic instrument port as part of their planned surgery. After surgery at 4 and 24 hours the patient will be asked to rate their pain on a simple chart.
Corticosteroid
Depo-medrol +1 More for Restless Legs Syndrome
Recruiting2 awards4 criteria
Charleston, South Carolina
The purpose of this study is to determine whether, in a randomized, placebo-controlled trial, restless legs syndrome (RLS) can be caused by pinched and damaged foot nerves called neuromas.
PCA and pump with saline infusion for up to five days for Laparoscopic Surgery
Recruiting1 awardPhase 2
Hamilton, Ontario
The incisions used in abdominal surgery can be quite painful, requiring strong pain medications. A new pain pump that trickles small amounts of local freezing into the incision has been developed that helps numb the area so that the patient does not feel the pain for two to five days after surgery. The main research question is whether use of the pain pump will result in decreased hospital length of stay. The research is important because if the pain pump is found to be effective, it can substantially decrease the length of stay. Areas to be studied include hospital length of stay, patient's comfort post-operatively, and post-operative complications.
Local for Appendicitis
Recruiting0 awards1 criteria
Phoenix, Arizona
Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random. The clinical hypothesis of this trial is that pediatric patients who undergo a local anesthetic pre-incisional and/or post-incisional will reduce the amount of postoperative pain and therefore reduce the amount of analgesics required to keep the patient satisfied. Primary: To determine if local anesthetic reduces postoperative pain. Secondary: To assess the timing of local anesthetic injection affects postoperative pain.
Local Anesthetic
Ultrasound-Guided Nerve Block for Hip Fractures
Recruiting3 awards
Boston, Massachusetts
This trial will compare pain control in people with hip fractures who receive ultrasound-guided femoral nerve blocks to those who receive the standard pain management of an injection of opioid medication.
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Phase 3 Trials
Local Anesthetic
Bupivacaine for Graves Disease
Recruiting3 awardsPhase 2 & 3
San Francisco, California
This trial will test if a bupivacaine injection into eye muscles can make them stronger to fix mis-aligned or turned in eyes, strabismus. Different concentrations and formulations of bupivacaine will be tested as well as if Botox added to other eye muscles can help the effect.
Local Anesthetic
Continuous bupivacaine analgesia infusion for Pelvic Organ Prolapse
Recruiting1 awardPhase 2 & 3
Kansas City, Missouri
This prospective randomized controlled study will determine the efficacy of continuous local anesthesia at decreasing pain scores compared to patient controlled analgesia for pelvic organ prolapse procedures including posterior colporrhaphy and sacrospinous ligament fixation.
Local Anesthetic
Femoral Nerve Block Bupivacaine +1 More for Pain
Recruiting4 awardsPhase 3
Boston, Massachusetts
The main objective of the study is to determine if intrarticular injection with liposomal bupivicaine (Exparel) provides better postoperative pain relief and functional outcome following total knee replacement (TKR) than the current standard New England Baptist Hospital regimen of femoral nerve block combined with intraarticular injection of a standard bupivicaine solution.
Liposomal Bupivicaine in TAP block for Postoperative Pain
Recruiting4 awardsPhase 3
Abington, Pennsylvania
This study evaluates the comparison between liposomal bupivacaine versus bupivacaine HCl in Transversus Abdominis Plane blocks for gynecologic surgery on the length of stay in the hospital, total narcotic use, and overall complications rates.
Trials With No Placebo
Local Anesthetic
Bupivacaine +1 More for Low Blood Pressure
Recruiting3 awardsPhase 2
Montreal, Quebec
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension. The higher the spread of the blockade will result in a higher incidence of hypotension. Injected hyperbaric medication has about 15 minutes to spread within the intrathecal space before it will be taken up by the nerve roots. The time that a patient remains in one position after medication injection will affect the spread of the resultant anesthetic block. A patient who is left sitting for a longer period of time after injection of hyperbaric medication will have a lower level of block than someone who is placed supine immediately. In this study, the investigators wish to use up down sequential analysis to determine the time period a patient should remain seated after intrathecal injection of hyperbaric bupivacaine and fentanyl that will result in a 50% rate of hypotension.
Local Anesthetic
Bupivacaine for Graves Disease
Recruiting3 awardsPhase 2 & 3
San Francisco, California
This trial will test if a bupivacaine injection into eye muscles can make them stronger to fix mis-aligned or turned in eyes, strabismus. Different concentrations and formulations of bupivacaine will be tested as well as if Botox added to other eye muscles can help the effect.
Local Anesthetic
Bupivacaine Epidural +1 More for Pain
Recruiting3 awards1 criteria
Long Beach, California
The investigators intend to perform a large randomized trial using standardized obstetrical and anesthetic practice at a single institution to determine the effects of patient controlled epidural analgesia on obstetrical and neonatal outcomes.
Local Anesthetic
Continuous bupivacaine analgesia infusion for Pelvic Organ Prolapse
Recruiting1 awardPhase 2 & 3
Kansas City, Missouri
This prospective randomized controlled study will determine the efficacy of continuous local anesthesia at decreasing pain scores compared to patient controlled analgesia for pelvic organ prolapse procedures including posterior colporrhaphy and sacrospinous ligament fixation.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.