Trials in Baltimore, Maryland
Here are the top 10 medical studies for glioblastoma in Baltimore, Maryland
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Phase 3 Trials
Alkylating agents
Lomustine + Standard Therapy for Glioblastoma
Recruiting2 awardsPhase 3
Baltimore, Maryland
This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.
Chemotherapy
Ultrasound-Assisted Chemotherapy for Glioblastoma
Recruiting2 awardsPhase 3
Baltimore, Maryland
This trial tests a new method to treat recurrent brain cancer using an ultrasound device called SonoCloud-9. The device helps open the brain's protective barrier so that more of the chemotherapy drug carboplatin can reach the tumor. The goal is to see if this combination makes the treatment more effective. Carboplatin has been used in various studies for treating high-grade gliomas and glioblastomas, often showing modest efficacy due to low tissue concentration when delivered intravenously.
Alkylating agents
Multiple Therapies for Glioblastoma
Recruiting1 awardPhase 2 & 3
Philadelphia, Pennsylvania
This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.
Dendritic cell immunotherapy
Immunotherapy with DCVax-L for Brain Cancer
Recruiting1 awardPhase 3
Washington, District of Columbia
This trial tests DCVax-L, a treatment using a patient's own immune cells, in patients with newly diagnosed GBM undergoing surgery. It aims to train their immune system to better attack brain cancer cells. This treatment is being tested in several clinical trials, with safety and feasibility proven and promising clinical results reported.
Trials With No Placebo
Alkylating agents
Lomustine + Standard Therapy for Glioblastoma
Recruiting2 awardsPhase 3
Baltimore, Maryland
This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.
Monoclonal Antibodies
Carmustine + Retifanlimab + Radiation for Glioblastoma
Recruiting1 awardPhase 1
Baltimore, Maryland
This trial is testing a combination of treatments including carmustine wafers, radiation, retifanlimab, and possibly temozolomide in adults newly diagnosed with glioblastoma multiforme. The goal is to see if these treatments are safe and help patients live longer. The treatments work by directly targeting the tumor, damaging cancer cells' DNA, and boosting the immune system to fight the cancer. Carmustine wafers have been shown to be an effective addition to standard treatment in glioblastoma, with a significant survival benefit.
Alkylating agents
Stem Cell Rescue Therapy for Glioblastoma
Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is studying the effect of giving P140K MGMT hematopoietic stem cells, O6-benzylguanine, temozolomide, and carmustine to people with supratentorial glioblastoma or gliosarcoma who have recently had surgery to remove most or all of the brain tumor (resected).
Cancer Vaccine
SurVaxM Vaccine for Brain Cancer
Recruiting1 awardPhase 1
Washington, District of Columbia
This trial tests the SurVaxM vaccine, which helps the immune system target and destroy cancer cells, in children and young adults with certain difficult-to-treat brain cancers. The vaccine works by teaching the immune system to recognize a protein found in cancer cells. Additional substances are used to make the immune response stronger.
Monoclonal Antibodies
NGM707 + Pembrolizumab for Cancer
Recruiting1 awardPhase 1 & 2
Baltimore, Maryland
This trial is testing a new drug called NGM707, both by itself and with another drug, Pembrolizumab. It targets patients with very advanced or spreading solid tumors. The treatment aims to boost the immune system to better fight cancer.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.