Popular Trials
Shoonya Meditation for Sleep Deprivation
This trial investigates if regular meditation can help people who don't get enough sleep by improving heart function and relaxation. The study will compare cognitive performance and sleep quality between those who meditate and those who don't.
Cannabinoid
Cannabis for Cancer-Related Symptoms
This trial will test the effectiveness of three cannabis oil extract combinations (High THC-Low CBD, Low THC-High CBD, or Equal amounts of THC and CBD) in a minimum of 120 cancer patients on 4 cancer-related symptoms: nausea, pain, anxiety and sleep disturbance.
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Trials for Insomnia Patients
Behavioural Intervention
CBT + Trazodone for Insomnia
This trial aims to compare how individuals with insomnia and short sleep duration differ from those with normal sleep duration in terms of health risks and response to treatment. The study will investigate the effectiveness of two common insomnia
Behavioral Intervention
Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin) +2 More for Insomnia
The primary objective of the current study is to determine if providing cognitive-behavioral therapy of Insomnia and nightmares (CBTin) and Cognitive Processing Therapy of PTSD (CPT) results in greater PTSD and sleep symptom reduction than CPT only. A secondary objective is to determine if the sequencing of CBTl\&N before or after CPT results in differential effects on PTSD and sleep symptom reduction.
Hormone Therapy
Melatonin for Sleep Disorders
The study will evaluate the safety and efficacy of melatonin supplementation in CKD and ESRD patients with sleep disorders to reduce sleep latency times, the number of apnea/hypopneic episodes, and prolong duration in rapid eye movement (REM) sleep in CKD and ESRD patients with sleep disordered breathing.
Melatonin Receptor Agonist
Tasimelteon for Autism and Sleep Disorders
This trial is testing a daily pill called tasimelteon to help children and adults with Autism Spectrum Disorder (ASD) who have trouble sleeping. The medication aims to improve sleep by helping to regulate the body's internal clock.
Behavioural Intervention
Insomnia Therapy for Cardiovascular Disease Improvement
This trial will test if an updated insomnia treatment improves CVD factors & if this is due to improved sleep. 200 participants will get either the treatment or an active control. Results will be measured for CVD factors & sleep.
Trials for Sleep Apnea Patients
Hormone Therapy
Melatonin for Sleep Disorders
The study will evaluate the safety and efficacy of melatonin supplementation in CKD and ESRD patients with sleep disorders to reduce sleep latency times, the number of apnea/hypopneic episodes, and prolong duration in rapid eye movement (REM) sleep in CKD and ESRD patients with sleep disordered breathing.
Diagnostic Test
Home vs Lab Sleep Apnea Testing for Sleep Apnea
This trial will compare home sleep apnea testing to in-lab polysomnography to see which is more accurate, leads to better decisions about treatment, and is more acceptable to parents and children.
Melatonin Receptor Agonist
Tasimelteon for Autism and Sleep Disorders
This trial is testing a daily pill called tasimelteon to help children and adults with Autism Spectrum Disorder (ASD) who have trouble sleeping. The medication aims to improve sleep by helping to regulate the body's internal clock.
Trials With No Placebo
Sleep Management for Nicotine Addiction
This trial will test the hypothesis that chronotype (preference for morning or evening activity) and impaired sleep impact cigarette usage, smoking dependence, urge/craving, and withdrawal differently in blacks compared to whites.
Behavioral Intervention
Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin) +2 More for Insomnia
The primary objective of the current study is to determine if providing cognitive-behavioral therapy of Insomnia and nightmares (CBTin) and Cognitive Processing Therapy of PTSD (CPT) results in greater PTSD and sleep symptom reduction than CPT only. A secondary objective is to determine if the sequencing of CBTl\&N before or after CPT results in differential effects on PTSD and sleep symptom reduction.
Hormone Therapy
Melatonin for Sleep Disorders
The study will evaluate the safety and efficacy of melatonin supplementation in CKD and ESRD patients with sleep disorders to reduce sleep latency times, the number of apnea/hypopneic episodes, and prolong duration in rapid eye movement (REM) sleep in CKD and ESRD patients with sleep disordered breathing.
Behavioural Intervention
Light Therapy for Circadian Rhythm Disorder
Jet lag and some sleep disorders are caused by a disruption in an individual's "internal clock." Understanding the most effective way to quickly re-adjust the body's internal clock will be beneficial for treating individuals with these conditions. This study will evaluate the combined effectiveness of light and non-light therapies at regulating sleep cycles and improving sleep quality.
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Frequently Asked Questions
Introduction to sleep disorder
What are the top hospitals conducting sleep disorder research?
When it comes to clinical trials for sleep disorders, several top hospitals are making strides in the field. The University of Michigan in Ann Arbor is leading the way with an active trial focused on sleep disorders, along with three previously conducted studies. This renowned institution began its journey into understanding these conditions through clinical trials in 2019, and their ongoing efforts continue to shed light on this complex area of medicine. Meanwhile, at the Washington University School of Medicine in Saint Louis and the University of Virginia in Charlottesville, researchers are also dedicated to unraveling the mysteries behind sleep disorders. Both institutions have one active trial each as well as a couple of previous investigations under their belts. These recent initiatives highlight their commitment to advancing knowledge and improving treatment options for those struggling with sleep-related difficulties.
In addition to academic institutions, we find John D Dingell VAMC contributing significantly towards research on sleep disorders; located in Detroit they host an active clinical investigation pertaining solely to this subject matter. While they may not boast any completed trials yet, their unwavering dedication brings fresh hope to patients seeking effective interventions for better quality slumber nights.
These hospitals across different locations showcase how medical professionals from various corners of the country are coming together to explore novel ways of diagnosing and treating various sleep disorders such as insomnia or narcolepsy that affect millions worldwide every day. By conducting rigorous clinical trials and pushing boundaries within this realm of healthcare discovery, these institutions hold promise not only for patients who currently suffer but also those who will benefit from future breakthroughs aimed at improving overall well-being through better sleep hygiene practices
Which are the best cities for sleep disorder clinical trials?
Detroit, Michigan and Boston, Massachusetts emerge as the leading cities for sleep disorder clinical trials. Detroit hosts 2 active trials investigating Hyperoxia and other related areas. Meanwhile, Boston also offers 2 ongoing studies focused on Shoonya Meditators, Tasimelteon, and additional topics of interest. These cities provide promising opportunities for individuals seeking participation in cutting-edge research aimed at advancing our understanding and treatment of sleep disorders.
Which are the top treatments for sleep disorder being explored in clinical trials?
Clinical trials are actively exploring different treatments for sleep disorders, with one treatment in particular showing promise. Tasimelteon has emerged as a top contender, currently being tested in an active trial dedicated to sleep disorders. Introduced just last year in 2020, it is the focus of this innovative research aimed at improving the management and treatment of these conditions. As researchers delve deeper into understanding sleep disorders, tasimelteon may offer new hope for those struggling with disrupted sleep patterns.
What are the most recent clinical trials for sleep disorder?
New clinical trials offer hope for individuals struggling with sleep disorders, exploring potential treatments that could improve their quality of life. One such trial involves the use of tasimelteon in addressing sleep disorders. This Phase 3 study, which became available on 12/9/2020, aims to evaluate the efficacy and safety of this medication. Additionally, hyperoxia has shown promising results in earlier phases (Phase 1 and Phase 2) as a potential treatment for sleep disorder patients. These recent trials shed light on innovative approaches to address this prevalent issue and may pave the way for improved therapies in the future.
What sleep disorder clinical trials were recently completed?
Recently, several clinical trials investigating sleep disorders have reached completion, paving the way for potential advancements in treatment. These trials address a range of sleep-related conditions and provide valuable insights into improving patient outcomes. Notable among these studies is a trial focused on insomnia medication sponsored by Stanford University School of Medicine which concluded in February 2021. Additionally, a trial examining the effectiveness of cognitive-behavioral therapy for sleep apnea was completed at Harvard Medical School in July 2021. The culmination of these rigorous investigations signifies significant progress towards enhancing our understanding and management of various sleep disorders.